Burkholderia pseudomallei K96243, BPSL0801 (purK)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006189 'de novo' IMP biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01161
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046872 metal ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50975
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004638 phosphoribosylaminoimidazole carboxylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01161
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PS50975
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bps01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00230 Purine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit 16 379 40.596
SUPERFAMILY SSF56059 112 314 1.62E-56
Gene3D G3DSA:3.30.1490.20 IPR013815 ATP-grasp fold, subdomain 1 122 193 2.5E-23
SUPERFAMILY SSF52440 IPR016185 Pre-ATP-grasp domain superfamily 8 109 2.45E-25
Gene3D G3DSA:3.30.470.20 194 395 4.6E-84
TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit 17 381 8.2E-115
ProSiteProfiles PS50975 ATP-grasp fold profile. IPR011761 ATP-grasp fold 117 307 36.525
Pfam PF17769 Phosphoribosylaminoimidazole carboxylase C-terminal domain IPR040686 Phosphoribosylaminoimidazole carboxylase, C-terminal domain 320 382 5.6E-20
SUPERFAMILY SSF51246 IPR011054 Rudiment single hybrid motif 317 393 1.1E-15
Pfam PF02222 ATP-grasp domain IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type 122 294 5.0E-47
Gene3D G3DSA:3.40.50.20 9 121 2.6E-41

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.