Burkholderia pseudomallei K96243, BPSL0799 (hemH)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0006164 | purine nucleotide biosynthetic process |
Inferred from Sequence Model
Term mapped from: InterPro:PS01058
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004639 | phosphoribosylaminoimidazolesuccinocarboxamide synthase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PS01058
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | bps01110 | Biosynthesis of secondary metabolites | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | bps00230 | Purine metabolism | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | inosine-5'-phosphate biosynthesis I | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bps01130 | Biosynthesis of antibiotics | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG (InterPro) | 00230 | Purine metabolism | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
|
| MetaCyc | inosine-5'-phosphate biosynthesis III | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
||
| KEGG | bps01100 | Metabolic pathways | 73.0+/03-31, Mar 15 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| MetaCyc | inosine-5'-phosphate biosynthesis II | InterPro 5.36-75.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| CDD | cd01414 | SAICAR_synt_Sc | 14 | 292 | 1.15844E-175 | ||
| TIGRFAM | TIGR00081 | purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase | IPR001636 | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 15 | 293 | 9.4E-81 |
| SUPERFAMILY | SSF56104 | 4 | 294 | 7.52E-106 | |||
| Gene3D | G3DSA:3.30.200.20 | 3 | 103 | 6.4E-32 | |||
| Hamap | MF_00137 | Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. | IPR028923 | SAICAR synthetase/ADE2, N-terminal | 12 | 292 | 25.518 |
| Gene3D | G3DSA:3.30.470.20 | 104 | 248 | 5.2E-59 | |||
| ProSitePatterns | PS01057 | SAICAR synthetase signature 1. | IPR018236 | SAICAR synthetase, conserved site | 105 | 119 | - |
| ProSitePatterns | PS01058 | SAICAR synthetase signature 2. | IPR018236 | SAICAR synthetase, conserved site | 204 | 212 | - |
| Pfam | PF01259 | SAICAR synthetase | IPR028923 | SAICAR synthetase/ADE2, N-terminal | 15 | 267 | 3.2E-102 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.