Burkholderia pseudomallei K96243, BPSL0779 (sucC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0779
Name
sucC
Replicon chromosome 1
Genomic location 906374 - 907540 (+ strand)

Cross-References

RefSeq YP_107404.1
GI 53718418
Entrez 3093010
GI 53718418
INSDC CAH34771.1
NCBI Locus Tag BPSL0779
RefSeq YP_107404.1,GeneID
UniParc UPI000043AD56
UniProtKB Acc Q63WW2
UniProtKB ID SUCC_BURPS
UniRef100 UniRef100_A3MH60
UniRef50 UniRef50_Q9KA20
UniRef90 UniRef90_Q13UH9

Product

Feature Type CDS
Coding Frame 1
Product Name
succinyl-CoA synthetase subunit beta
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (45.6 kDa, pI 4.67, PMID:21960737)
Charge (pH 7) -8.84
Kyte-Doolittle Hydrophobicity Value -0.018
Molecular Weight (kDa) 41285.3
Isoelectric Point (pI) 5.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 537 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002507 (652 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0779
Search term: sucC

Human Homologs

Ensembl 97, assembly GRCh38.p12
succinate-CoA ligase ADP-forming beta subunit [Source:HGNC Symbol;Acc:HGNC:11448]
E-value: 1.3e-96
Percent Identity: 48.3
Ensembl 97, assembly GRCh38.p12
succinate-CoA ligase ADP-forming beta subunit [Source:HGNC Symbol;Acc:HGNC:11448]
E-value: 1.3e-96
Percent Identity: 48.3

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268