Burkholderia pseudomallei K96243, BPSL0442

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0442
Name
Replicon chromosome 1
Genomic location 482135 - 483709 (- strand)

Cross-References

RefSeq YP_107067.1
GI 53718081
Entrez 3092719
GI 53718081
INSDC CAH34430.1
NCBI Locus Tag BPSL0442
RefSeq YP_107067.1,GeneID
UniParc UPI000043AC07
UniProtKB Acc Q63XU8
UniProtKB ID Q63XU8_BURPS
UniRef100 UniRef100_A0A097XXS3
UniRef50 UniRef50_Q0KET9
UniRef90 UniRef90_A1UZY0

Product

Feature Type CDS
Coding Frame 1
Product Name
C-terminal processing protease-3
Synonyms
Evidence for Translation
Charge (pH 7) 6.74
Kyte-Doolittle Hydrophobicity Value -0.407
Molecular Weight (kDa) 57068.5
Isoelectric Point (pI) 9.55

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 505 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002704 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0442

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268