Burkholderia pseudomallei K96243, BPSL0386 (metH2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0047150 betaine-homocysteine S-methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF037505
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008270 zinc ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF037505
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009086 methionine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF037505
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bps01230 Biosynthesis of amino acids 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00450 Selenocompound metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00270 Cysteine and methionine metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bps00670 One carbon pool by folate 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PIRSF PIRSF037505 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT 234 354 1.7E-4
PIRSF PIRSF037505 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT 72 244 2.4E-6
ProSiteProfiles PS50970 Homocysteine-binding domain profile. IPR003726 Homocysteine-binding domain 23 343 55.162
Pfam PF02574 Homocysteine S-methyltransferase IPR003726 Homocysteine-binding domain 35 343 2.0E-80
SUPERFAMILY SSF82282 IPR036589 Homocysteine-binding domain superfamily 26 353 8.11E-102
Gene3D G3DSA:3.20.20.330 IPR036589 Homocysteine-binding domain superfamily 21 358 3.6E-130

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.