Burkholderia pseudomallei K96243, BPSL0385 (metH1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0385
Name
metH1
Replicon chromosome 1
Genomic location 416706 - 419408 (- strand)

Cross-References

RefSeq YP_107011.1
GI 53718025
Entrez 3091951
GI 53718025
NCBI Locus Tag BPSL0385
RefSeq YP_107011.1,GeneID
UniProtKB Acc Q63Y04
UniProtKB ID Q63Y04_BURPS

Product

Feature Type CDS
Coding Frame 1
Product Name
5-methyltetrahydrofolate--homocysteine methyltransferase
Synonyms
Evidence for Translation
Charge (pH 7) -15.76
Kyte-Doolittle Hydrophobicity Value -0.075
Molecular Weight (kDa) 98820.1
Isoelectric Point (pI) 5.51

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 479 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002757 (647 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0385
Search term: metH1

Human Homologs

Ensembl 97, assembly GRCh38.p12
5-methyltetrahydrofolate-homocysteine methyltransferase [Source:HGNC Symbol;Acc:HGNC:7468]
E-value: 1.1e-260
Percent Identity: 53.1

References

No references are associated with this feature.