Burkholderia pseudomallei K96243, BPSL0366 (bioF)

Gene Feature Overview

Strain	Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1 GCF_000011545.1|latest
Locus Tag	BPSL0366
Name	bioF
Replicon	chromosome 1
Genomic location	394470 - 395654 (- strand)

Cross-References

RefSeq	YP_106992.1
GI	53718006
Entrez	3093351
GI	53718006
INSDC	CAH34354.1
NCBI Locus Tag	BPSL0366
RefSeq	YP_106992.1,GeneID
UniParc	UPI000043ABBC
UniProtKB Acc	Q63Y23
UniProtKB ID	BIOF_BURPS
UniRef100	UniRef100_A3MNG3
UniRef50	UniRef50_Q1GZA7
UniRef90	UniRef90_Q3JWR6

Product

Feature Type	CDS
Coding Frame	1
Product Name	8-amino-7-oxononanoate synthase
Synonyms
Evidence for Translation
Charge (pH 7)	0.48
Kyte-Doolittle Hydrophobicity Value	0.224
Molecular Weight (kDa)	40698.6
Isoelectric Point (pI)	7.07

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 507 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG002772 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BPSL0366 Search term: bioF Search term: 8-amino-7-oxononanoate synthase

Human Homologs

Ensembl 97, assembly GRCh38.p12	ENSP00000379501 5'-aminolevulinate synthase 2 [Source:HGNC Symbol;Acc:HGNC:397] E-value: 4.6e-41 Percent Identity: 34.0
Ensembl 97, assembly GRCh38.p12	ENSP00000337131 5'-aminolevulinate synthase 2 [Source:HGNC Symbol;Acc:HGNC:397] E-value: 4.6e-41 Percent Identity: 34.0
Ensembl 97, assembly GRCh38.p12	ENSP00000497236 5'-aminolevulinate synthase 2 [Source:HGNC Symbol;Acc:HGNC:397] E-value: 4.6e-41 Percent Identity: 34.0

References