Burkholderia pseudomallei K96243, BPSL0364 (bioB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009102 biotin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00433
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004076 biotin synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00433
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF04055
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051536 iron-sulfur cluster binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF04055
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bps01100 Metabolic pathways 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG (InterPro) 00780 Biotin metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG bps00780 Biotin metabolism 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc biotin biosynthesis from 8-amino-7-oxononanoate II InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PIRSF PIRSF001619 IPR024177 Biotin synthase 7 338 2.2E-136
SUPERFAMILY SSF102114 25 330 1.57E-92
CDD cd01335 Radical_SAM 69 254 4.44472E-20
Gene3D G3DSA:3.20.20.70 IPR013785 Aldolase-type TIM barrel 24 333 2.6E-127
SMART SM00876 IPR010722 Biotin and thiamin synthesis-associated domain 239 331 1.8E-46
TIGRFAM TIGR00433 bioB: biotin synthase IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 34 329 6.2E-125
Pfam PF04055 Radical SAM superfamily IPR007197 Radical SAM 69 221 6.1E-17
SFLD SFLDG01060 BATS domain containing 21 336 0.0
SMART SM00729 IPR006638 Elp3/MiaB/NifB 62 274 6.0E-38
Pfam PF06968 Biotin and Thiamin Synthesis associated domain IPR010722 Biotin and thiamin synthesis-associated domain 239 329 4.5E-18
Hamap MF_01694 Biotin synthase [bioB]. IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB 24 332 42.271
SFLD SFLDF00272 biotin synthase IPR024177 Biotin synthase 21 336 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.