Burkholderia pseudomallei K96243, BPSL0312 (glmS1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0312
Name
glmS1
Replicon chromosome 1
Genomic location 331614 - 333446 (- strand)

Cross-References

RefSeq YP_106939.1
GI 53717953
Entrez 3091987
GI 53717953
INSDC CAH34301.1
NCBI Locus Tag BPSL0312
RefSeq YP_106939.1,GeneID
UniParc UPI000043AB88
UniProtKB Acc Q63Y76
UniProtKB ID Q63Y76_BURPS
UniRef100 UniRef100_A0A097XTP1
UniRef50 UniRef50_Q9HT25
UniRef90 UniRef90_Q2T1V3

Product

Feature Type CDS
Coding Frame 1
Product Name
glucosamine--fructose-6-phosphate aminotransferase
Synonyms
Evidence for Translation
Charge (pH 7) -7.91
Kyte-Doolittle Hydrophobicity Value 0.040
Molecular Weight (kDa) 65860.5
Isoelectric Point (pI) 6.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 649 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002814 (2118 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0312
Search term: glmS1

Human Homologs

Ensembl 97, assembly GRCh38.p12
glutamine--fructose-6-phosphate transaminase 1 [Source:HGNC Symbol;Acc:HGNC:4241]
E-value: 9.8e-99
Percent Identity: 35.5

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268