Burkholderia pseudomallei K96243, BPSL0249 (dppA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0249
Name
dppA
Replicon chromosome 1
Genomic location 259630 - 261258 (+ strand)

Cross-References

RefSeq YP_106876.1
GI 53717890
Entrez 3091878
GI 53717890
INSDC CAH34237.1
NCBI Locus Tag BPSL0249
RefSeq YP_106876.1,GeneID
UniParc UPI000043AB4A
UniProtKB Acc Q63YD9
UniProtKB ID Q63YD9_BURPS
UniRef100 UniRef100_Q3JX52
UniRef50 UniRef50_Q4KIC0
UniRef90 UniRef90_Q3JX52

Product

Feature Type CDS
Coding Frame 1
Product Name
periplasmic dipeptide transport protein
Synonyms
Evidence for Translation
Charge (pH 7) 9.57
Kyte-Doolittle Hydrophobicity Value -0.305
Molecular Weight (kDa) 60412.7
Isoelectric Point (pI) 9.23

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 551 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002870 (941 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0249
Search term: dppA

Human Homologs

References

Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268