Burkholderia cenocepacia K56-2, WQ49_RS04260 (paaH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0010124 phenylacetate catabolic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P77467
ECO:00000060
12846838 Reviewed by curator
Molecular Function GO:0008691 3-hydroxybutyryl-CoA dehydrogenase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P77467
ECO:00000060
20660314 Reviewed by curator
Molecular Function GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P77467
ECO:00000060
20660314 Reviewed by curator
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF48179
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02737
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006631 fatty acid metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02737
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02737
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.750.190 304 427 5.7E-89
SUPERFAMILY SSF51735 IPR036291 NAD(P)-binding domain superfamily 20 199 2.73E-52
Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal 200 297 1.3E-29
Gene3D G3DSA:3.40.50.720 17 203 2.9E-63
Gene3D G3DSA:1.10.1040.50 204 506 5.7E-89
Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal 430 514 1.2E-16
SUPERFAMILY SSF48179 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily 199 302 3.32E-30
Pfam PF18321 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain IPR041040 3-hydroxybutyryl-CoA dehydrogenase reduced Rossmann-fold domain 360 429 6.9E-21
Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding 20 197 3.1E-58
SUPERFAMILY SSF48179 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily 429 514 2.55E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.