Burkholderia pseudomallei K96243, BPSL0007 (gspD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0007
Name
gspD
Replicon chromosome 1
Genomic location 8395 - 10668 (+ strand)

Cross-References

RefSeq YP_106632.1
GI 53717646
Entrez 3091427
GI 53717646
INSDC CAH33990.1
NCBI Locus Tag BPSL0007
RefSeq YP_106632.1,GeneID
UniParc UPI000043AA60
UniProtKB Acc Q63Z30
UniProtKB ID Q63Z30_BURPS
UniRef100 UniRef100_I1WEJ1
UniRef50 UniRef50_A1V993
UniRef90 UniRef90_A1V993

Product

Feature Type CDS
Coding Frame 1
Product Name
general secretory pathway protein D
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724). Found in at least two preparations.
Charge (pH 7) 3.22
Kyte-Doolittle Hydrophobicity Value -0.102
Molecular Weight (kDa) 78354.8
Isoelectric Point (pI) 8.98

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 343 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000049 (640 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0007
Search term: gspD

Human Homologs

References

Molecular characterization of genetic loci required for secretion of exoproducts in Burkholderia pseudomallei.
DeShazer D, Brett PJ, Burtnick MN, Woods DE
J Bacteriol 1999 Aug;181(15):4661-4
PubMed ID: 10419967