Burkholderia pseudomallei K96243, BPSL0004 (hupA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest
Locus Tag
BPSL0004
Name
hupA
Replicon chromosome 1
Genomic location 5488 - 5766 (+ strand)

Cross-References

RefSeq YP_106629.1
GI 53717643
Entrez 3091972
GI 53717643
INSDC CAH33987.1
NCBI Locus Tag BPSL0004
RefSeq YP_106629.1,GeneID
UniParc UPI0000128EF2
UniProtKB Acc P0DMK4
UniProtKB ID DBHA_BURPS
UniRef100 UniRef100_I1WEI8
UniRef50 UniRef50_I1WEI8
UniRef90 UniRef90_I1WEI8

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA-binding protein HU-alpha
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (13.1 kDa, pI 4.48, PMID:21960737)
Charge (pH 7) 8.98
Kyte-Doolittle Hydrophobicity Value -0.386
Molecular Weight (kDa) 9621.0
Isoelectric Point (pI) 10.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6N2L DNA BINDING PROTEIN 11/13/18 Crystal structure of a histone family protein DNA-binding protein from Burkholderia ambifaria BURKHOLDERIA AMBIFARIA (STRAIN MC40-6) 1.85 X-RAY DIFFRACTION 98.9

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 569 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000052 (653 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSL0004
Search term: hupA

Human Homologs

References

No references are associated with this feature.