Burkholderia pseudomallei K96243, BPSL0003 (mnmC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008168 methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR03197
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004808 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01102
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01266
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01266
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF05430
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008033 tRNA processing
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_01102
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc tRNA-uridine 2-thiolation (bacteria) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.9.10 347 567 1.8E-117
Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase IPR008471 MnmC-like methyltransferase 122 240 2.5E-35
Gene3D G3DSA:3.40.50.150 8 249 1.1E-89
Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC 6 652 24.864
SUPERFAMILY SSF51905 IPR036188 FAD/NAD(P)-binding domain superfamily 262 655 4.66E-29
SUPERFAMILY SSF54373 480 564 4.32E-10
Pfam PF01266 FAD dependent oxidoreductase IPR006076 FAD dependent oxidoreductase 262 627 3.6E-41
TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal 262 657 2.6E-125
Gene3D G3DSA:3.50.50.60 IPR036188 FAD/NAD(P)-binding domain superfamily 261 654 1.8E-117

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.