Strain |
Burkholderia cenocepacia H111
GCF_000236215.2|latest |
Locus Tag |
I35_RS18940
|
NCBI Old Locus Tag | I35_2279%2CI35_4475 |
Name |
dfsA
Synonym: rpfF |
Replicon | chromosome 2 |
Genomic location | 547031 - 547894 (- strand) |
RefSeq | WP_006488766.1 |
GI | 493534800 |
NCBI Locus Tag | I35_RS18940 |
NCBI Old Locus Tag | I35_2279%2CI35_4475 |
RefSeq | WP_006488766.1 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
diffusible factor synthase A
|
Synonyms |
enoyl-CoA hydratase |
Evidence for Translation | |
Charge (pH 7) | -3.68 |
Kyte-Doolittle Hydrophobicity Value | 0.006 |
Molecular Weight (kDa) | 32000.4 |
Isoelectric Point (pI) | 5.97 |
Individual Mappings | |
Additional evidence for subcellular localization |
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
5FUS | LYASE | 01/29/16 | Crystal structure of B. cenocepacia DfsA | BURKHOLDERIA CENOCEPACIA | 1.87 | X-RAY DIFFRACTION | 100.0 |
6DGN | UNKNOWN FUNCTION | 05/17/18 | Cronobacter turicensis BDSF synthase RpfF in complex with the RpfR quorum-sensing receptor FI domain | BURKHOLDERIA CENOCEPACIA PC184; CRONOBACTER TURICENSIS (STRAIN DSM 18703 / LMG 23827 / Z3032) | 1.999 | X-RAY DIFFRACTION | 99.3 |
Results | Analysis not done |
Burkholderia Ortholog Group |
BG004647 (313 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: I35_RS18940
Search term: dfsA
Search term: diffusible factor synthase A
|
A novel DSF-like signal from Burkholderia cenocepacia interferes with Candida albicans morphological transition.
Boon C, Deng Y, Wang LH, He Y, Xu JL, Fan Y, Pan SQ, Zhang LH
ISME J 2008 Jan;2(1):27-36
PubMed ID: 18049456
|
Quorum sensing systems influence Burkholderia cenocepacia virulence.
Subramoni S, Sokol PA
Future Microbiol 2012 Dec;7(12):1373-87
PubMed ID: 23231487
|
The host plant metabolite glucose is the precursor of diffusible signal factor (DSF) family signals in Xanthomonas campestris.
Deng Y, Liu X, Wu J, Lee J, Chen S, Cheng Y, Zhang C, Zhang LH
Appl Environ Microbiol 2015 Apr;81(8):2861-8
PubMed ID: 25681189
|
The DSF type quorum sensing signalling system RpfF/R regulates diverse phenotypes in the opportunistic pathogen Cronobacter.
Suppiger A, Eshwar AK, Stephan R, Kaever V, Eberl L, Lehner A
Sci Rep 2016 Jan 4;6:18753
PubMed ID: 26725701
|
The Burkholderia cenocepacia BDSF quorum sensing fatty acid is synthesized by a bifunctional crotonase homologue having both dehydratase and thioesterase activities.
Bi H, Christensen QH, Feng Y, Wang H, Cronan JE
Mol Microbiol 2012 Feb;83(4):840-55
PubMed ID: 22221091
|