Burkholderia cenocepacia H111, I35_RS15965

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia H111
GCF_000236215.2|latest
Locus Tag
I35_RS15965
NCBI Old Locus TagI35_1776%2CI35_3194
Name
Replicon chromosome 1
Genomic location 3440712 - 3443126 (- strand)
CommentRequired for growth in the presence of 20__M CuSO4 (PMID:32090500)

Cross-References

RefSeq WP_034178451.1
GI 736004533
NCBI Locus Tag I35_RS15965
NCBI Old Locus Tag I35_1776%2CI35_3194
RefSeq WP_034178451.1

Product

Feature Type CDS
Coding Frame 1
Product Name
histidine kinase
Synonyms
Evidence for Translation
Charge (pH 7) 7.68
Kyte-Doolittle Hydrophobicity Value 0.027
Molecular Weight (kDa) 86780.9
Isoelectric Point (pI) 9.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG002949 (644 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: I35_RS15965
Search term: histidine kinase

Human Homologs

References

Copper resistance genes of Burkholderia cenocepacia H111 identified by transposon sequencing.
Higgins S, Gualdi S, Pinto-Carbó M, Eberl L
Environ Microbiol Rep 2020 Apr;12(2):241-249
PubMed ID: 32090500