Burkholderia cenocepacia AU 1054, BCEN_RS14675 (putA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003700 DNA-binding transcription factor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000197
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0010133 proline catabolic process to glutamate
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000197
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000197
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006561 proline biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01238
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.309.10
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.309.10
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004657 proline dehydrogenase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000197
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055114 oxidation-reduction process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.309.10
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:1.10.1220.10
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
MetaCyc ethylene biosynthesis II (microbes) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00250 Alanine, aspartate and glutamate metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc (5<i>R</i>)-carbapenem carboxylate biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
MetaCyc L-<i>N<sup>&delta;</sup></i>-acetylornithine biosynthesis InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG (InterPro) 00330 Arginine and proline metabolism InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.20.20.220 218 600 1.9E-152
Pfam PF18327 Proline utilization A proline dehydrogenase N-terminal domain IPR041349 Proline utilization A proline dehydrogenase N-terminal domain 90 137 5.3E-21
Pfam PF01619 Proline dehydrogenase IPR002872 Proline dehydrogenase domain 267 563 2.0E-99
TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 600 1099 4.2E-242
SUPERFAMILY SSF47598 IPR010985 Ribbon-helix-helix 4 45 8.45E-9
SUPERFAMILY SSF81935 IPR024089 Proline dehydrogenase PutA, domain I/II 89 258 3.27E-65
ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. IPR016160 Aldehyde dehydrogenase, cysteine active site 901 912 -
SUPERFAMILY SSF51730 IPR029041 FAD-linked oxidoreductase-like 259 608 1.33E-121
Pfam PF14850 DNA-binding domain of Proline dehydrogenase IPR024082 Proline dehydrogenase PutA, domain II 145 256 2.9E-46
Pfam PF00171 Aldehyde dehydrogenase family IPR015590 Aldehyde dehydrogenase domain 652 1097 1.1E-113
Gene3D G3DSA:3.20.20.220 89 185 4.4E-18
Gene3D G3DSA:3.40.309.10 IPR016163 Aldehyde dehydrogenase, C-terminal 876 1068 8.1E-146
SUPERFAMILY SSF53720 IPR016161 Aldehyde/histidinol dehydrogenase 643 1099 1.83E-127
Gene3D G3DSA:3.40.605.10 IPR016162 Aldehyde dehydrogenase, N-terminal 629 1099 8.1E-146
Gene3D G3DSA:1.10.1220.10 IPR013321 Arc-type ribbon-helix-helix 11 52 5.1E-18
CDD cd07125 ALDH_PutA-P5CDH 556 1108 0.0
PIRSF PIRSF000197 IPR025703 Bifunctional protein PutA 75 1310 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.