Burkholderia ambifaria AMMD, BAMB_RS16935 (bceN)

Cytoplasmic Membrane
Outer Membrane
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Gene Feature Overview

Strain Burkholderia ambifaria AMMD - Assembly GCF_000203915.1
Locus Tag
NCBI Old Locus TagBamb_3358
Replicon chromosome 2
Genomic location 151956 - 153002 (- strand)
CommentMember of the bce-II gene cluster


RefSeq WP_011658392.1
GI 499977674
NCBI Locus Tag BAMB_RS16935
NCBI Old Locus Tag Bamb_3358
RefSeq WP_011658392.1


Feature Type CDS
Coding Frame NA
Product Name
GDP-D-mannose 4,6-dehydratase BceN
Product Name Confidence: Class 2
Synonyms GDP-mannose 4,6-dehydratase
Evidence for Translation
Charge (pH 7) -3.64
Kyte-Doolittle Hydrophobicity Value -0.360
Molecular Weight (kDa) 39104.0
Isoelectric Point (pI) 6.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003102 (653 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: BAMB_RS16935
Search term: bceN

Human Homologs

Ensembl 97, assembly GRCh38.p12
GDP-mannose 4,6-dehydratase [Source:HGNC Symbol;Acc:HGNC:4369]
E-value: 9.5e-99
Percent Identity: 52.8


Biochemical and functional studies on the Burkholderia cepacia complex bceN gene, encoding a GDP-D-mannose 4,6-dehydratase.
Sousa SA, Feliciano JR, Pinheiro PF, Leitão JH
PLoS One 2013;8(2):e56902
PubMed ID: 23460819
Distribution of cepacian biosynthesis genes among environmental and clinical Burkholderia strains and role of cepacian exopolysaccharide in resistance to stress conditions.
Ferreira AS, Leitão JH, Silva IN, Pinheiro PF, Sousa SA, Ramos CG, Moreira LM
Appl Environ Microbiol 2010 Jan;76(2):441-50
PubMed ID: 19948863