Burkholderia cenocepacia K56-2Valvano, BURCENK562V_RS12625 (tecA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia K56-2Valvano
GCF_000333155.2|latest
Locus Tag
BURCENK562V_RS12625
NCBI Old Locus TagBURCENK562V_C3992
Name
tecA
Replicon ctg7180000002940B
Genomic location 1496155 - 1496634 (- strand)

Cross-References

RefSeq WP_006489887.1
GI 493535936
GI 493535936
NCBI Locus Tag BURCENK562V_RS12625
NCBI Old Locus Tag BURCENK562V_C3992
RefSeq WP_006489887.1

Product

Feature Type CDS
Coding Frame 1
Product Name
type VI secretion system effector protein TecA
Product Name Confidence: Class 2
Synonyms urea amidohydrolase
Evidence for Translation
Charge (pH 7) 2.91
Kyte-Doolittle Hydrophobicity Value -0.046
Molecular Weight (kDa) 17031.1
Isoelectric Point (pI) 9.08

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 2
sequence similarity evidence used in manual assertion
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006635 (186 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: tecA

Human Homologs

References

A Burkholderia Type VI Effector Deamidates Rho GTPases to Activate the Pyrin Inflammasome and Trigger Inflammation.
Aubert DF, Xu H, Yang J, Shi X, Gao W, Li L, Bisaro F, Chen S, Valvano MA, Shao F
Cell Host Microbe 2016 May 11;19(5):664-74
PubMed ID: 27133449