Burkholderia pseudomallei 1026b, BP1026B_II1037 (penA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0030655 beta-lactam antibiotic catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00118
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0046677 response to antibiotic
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00118
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008800 beta-lactamase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00118
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Pathways

Database Xref Pathway Version Evidence PMID
KEGG bpz01501 beta-Lactam resistance 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bpz01130 Biosynthesis of antibiotics 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bpz01110 Biosynthesis of secondary metabolites 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG bpz00311 Penicillin and cephalosporin biosynthesis 73.0+/03-31, Mar 15 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PRINTS PR00118 Beta-lactamase class A signature IPR000871 Beta-lactamase, class-A 39 63 3.2E-72
Pfam PF13354 Beta-lactamase enzyme family 60 266 2.5E-42
PRINTS PR00118 Beta-lactamase class A signature IPR000871 Beta-lactamase, class-A 210 225 3.2E-72
SUPERFAMILY SSF56601 IPR012338 Beta-lactamase/transpeptidase-like 37 293 1.54E-79
PRINTS PR00118 Beta-lactamase class A signature IPR000871 Beta-lactamase, class-A 148 172 3.2E-72
PRINTS PR00118 Beta-lactamase class A signature IPR000871 Beta-lactamase, class-A 70 87 3.2E-72
PRINTS PR00118 Beta-lactamase class A signature IPR000871 Beta-lactamase, class-A 174 199 3.2E-72
PRINTS PR00118 Beta-lactamase class A signature IPR000871 Beta-lactamase, class-A 227 242 3.2E-72
Gene3D G3DSA:3.40.710.10 34 295 1.6E-82
ProSitePatterns PS00146 Beta-lactamase class-A active site. IPR023650 Beta-lactamase, class-A active site 72 87 -
PRINTS PR00118 Beta-lactamase class A signature IPR000871 Beta-lactamase, class-A 112 137 3.2E-72
Coils Coil 26 46 -

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.