Log of Annotation Updates

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Date Locus Tag Strain Description Submitter
Apr 30, 2018 BTH_II1231 Burkholderia thailandensis E264; ATCC 700388 New gene name: btaR2. New product name: BtaR2. New PubMed ID: 19376863. New PubMed ID: 21615115. New PubMed ID: 20095633. New comment: Belongs to the bactobolin biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BCAM1007 Burkholderia cenocepacia J2315 New gene name: bceQ. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4475. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0126 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssL-2. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BCAL0404 Burkholderia cenocepacia J2315 New gene name: paaK1. New product name: PaaK1. New product name synonym: phenylacetate-CoA ligase. New product name confidence: Class 1. New PubMed ID: 21388965. New comment: . Dustin Lavallee and Silvia Cardona, University of Manitoba
Apr 30, 2018 BTH_II1232 Burkholderia thailandensis E264; ATCC 700388 New gene name: btaJ. New product name: BtaJ. New PubMed ID: 19376863. New PubMed ID: 21615115. New PubMed ID: 20095633. New comment: Belongs to the bactobolin biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 AK34_RS06450 Burkholderia dolosa AU0158 New gene name: bceQ. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4475. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0127 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssM-2. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 WQ49_RS04255 Burkholderia cenocepacia K56-2 New gene name: paaK2. New product name: Paak2. New product name synonym: phenylacetate-CoA ligase. New product name confidence: Class 1. New PubMed ID: 21388965. New comment: . Dustin Lavallee and Silvia Cardona, University of Manitoba
Apr 30, 2018 BTH_II1233 Burkholderia thailandensis E264; ATCC 700388 New gene name: btaK. New product name: BtaK. New PubMed ID: 19376863. New PubMed ID: 21615115. New PubMed ID: 20095633. New comment: Belongs to the bactobolin biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BPSS1685 Burkholderia pseudomallei K96243 New gene name: bceQ. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4475. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0128 Burkholderia thailandensis E264; ATCC 700388 New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BURCENK562V_RS11890 Burkholderia cenocepacia K56-2Valvano New gene name: paaK2. New product name: Paak2. New product name synonym: phenylacetate-CoA ligase. New product name confidence: Class 1. New PubMed ID: 21388965. New comment: . Dustin Lavallee and Silvia Cardona, University of Manitoba
Apr 30, 2018 BTH_II1234 Burkholderia thailandensis E264; ATCC 700388 New gene name: btaL. New product name: BtaL. New PubMed ID: 19376863. New PubMed ID: 21615115. New PubMed ID: 20095633. New comment: Belongs to the bactobolin biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0694 Burkholderia thailandensis E264; ATCC 700388 New gene name: bceQ. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4475. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0129 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssI-2. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BCAM1711 Burkholderia cenocepacia J2315 New gene name: paaK2. New product name: Paak2. New product name synonym: phenylacetate-CoA ligase. New product name confidence: Class 1. New PubMed ID: 21388965. New comment: . Dustin Lavallee and Silvia Cardona, University of Manitoba
Apr 30, 2018 BTH_II1235 Burkholderia thailandensis E264; ATCC 700388 New gene name: btaM. New product name: BtaM. New PubMed ID: 19376863. New PubMed ID: 21615115. New PubMed ID: 20095633. New comment: Belongs to the bactobolin biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 bglu_2g08540 Burkholderia glumae BGR1 New gene name: bceQ. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4475. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0130 Burkholderia thailandensis E264; ATCC 700388 New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 WQ49_RS11515 Burkholderia cenocepacia K56-2 New gene name: paaI. New product name: PaaI. New product name synonym: putative phenylacetatyl-CoA thioesterase. New product name confidence: Class 2. New PubMed ID: 16464851. New comment: . Annotation transferred from: UniProtKB:P76084. Dustin Lavallee and Silvia Cardona, University of Manitoba
Apr 30, 2018 BTH_II1236 Burkholderia thailandensis E264; ATCC 700388 New gene name: btaN. New product name: BtaN. New PubMed ID: 19376863. New PubMed ID: 21615115. New PubMed ID: 20095633. New comment: Belongs to the bactobolin biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 Bmul_4609 Burkholderia multivorans ATCC 17616 New gene name: bceQ. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4475. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0131 Burkholderia thailandensis E264; ATCC 700388 New product name: Rhs-2. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 WQ49_RS09445 Burkholderia cenocepacia K56-2 New product name: putative (R)-specific oxepin-CoA hydratase. New product name synonym: PaaZ-ECH. New product name confidence: Class 2. New PubMed ID: 21296885. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P232. Dustin Lavallee and Silvia Cardona, University of Manitoba
Apr 30, 2018 BTH_II1237 Burkholderia thailandensis E264; ATCC 700388 New gene name: btaO. New product name: BtaO. New PubMed ID: 19376863. New PubMed ID: 21615115. New PubMed ID: 20095633. New comment: Belongs to the bactobolin biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BAMB_RS16950 Burkholderia ambifaria AMMD New gene name: bceQ. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4475. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0132 Burkholderia thailandensis E264; ATCC 700388 New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BURCENK562V_RS32320 Burkholderia cenocepacia K56-2Valvano New product name: putative (R)-specific oxepin-CoA hydratase. New product name synonym: PaaZ-ECH. New product name confidence: Class 2. New PubMed ID: 21296885. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P232. Dustin Lavallee and Silvia Cardona, University of Manitoba
Apr 30, 2018 BTH_II1238 Burkholderia thailandensis E264; ATCC 700388 New gene name: btaP. New product name: BtaP. New PubMed ID: 19376863. New PubMed ID: 21615115. New PubMed ID: 20095633. New comment: Belongs to the bactobolin biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 I35_RS21110 Burkholderia cenocepacia H111 New gene name: bceQ. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4475. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0133 Burkholderia thailandensis E264; ATCC 700388 New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BCAS0364 Burkholderia cenocepacia J2315 New product name: putative (R)-specific oxepin-CoA hydratase. New product name synonym: PaaZ-ECH. New product name confidence: Class 2. New PubMed ID: 21296885. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P232. Dustin Lavallee and Silvia Cardona, University of Manitoba
Apr 30, 2018 BTH_II1239 Burkholderia thailandensis E264; ATCC 700388 New gene name: btaQ. New product name: BtaQ. New PubMed ID: 19376863. New PubMed ID: 21615115. New PubMed ID: 20095633. New comment: Belongs to the bactobolin biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BURCENK562V_RS08365 Burkholderia cenocepacia K56-2Valvano New gene name: bceQ. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4475. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0134 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssA-2. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 AK34_RS09175 Burkholderia dolosa AU0158 New product name: putative (R)-specific oxepin-CoA hydratase. New product name synonym: PaaZ-ECH. New product name confidence: Class 2. New PubMed ID: 21296885. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P232. Geoff Winsor, Simon Fraser University. Transferred annotation from the B. cenocepacia annotation provided by D. Lavellee and S. Cardona.
Apr 30, 2018 BTH_II1240 Burkholderia thailandensis E264; ATCC 700388 New gene name: btaS. New product name: BtaS. New PubMed ID: 19376863. New PubMed ID: 21615115. New PubMed ID: 20095633. New comment: Belongs to the bactobolin biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BCEP18194_RS33305 Burkholderia lata 383 New gene name: bceQ. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4475. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0135 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssG-2. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 WQ49_RS11500 Burkholderia cenocepacia K56-2 New gene name: pacL. New product name: PacL. New product name synonym: putative 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase. New product name confidence: Class 2. New PubMed ID: 21296885. New PubMed ID: 18776009. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P3J4. Dustin Lavallee and Silvia Cardona, University of Manitoba
Apr 30, 2018 BTH_II1241 Burkholderia thailandensis E264; ATCC 700388 New gene name: btaT. New product name: BtaT. New PubMed ID: 19376863. New PubMed ID: 21615115. New PubMed ID: 20095633. New comment: Belongs to the bactobolin biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BCAM1008 Burkholderia cenocepacia J2315 New gene name: bceR. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. . New comment: Note that another gene (BCAM1493) for a two-component response regulator in B. cenocepacia J2315 was also assigned the name bceR at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4476. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0136 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssF-2. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BURCENK562V_RS28560 Burkholderia cenocepacia K56-2Valvano New gene name: pacL. New product name: PacL. New product name synonym: putative 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase. New product name confidence: Class 2. New PubMed ID: 21296885. New PubMed ID: 18776009. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P3J4. Dustin Lavallee and Silvia Cardona, University of Manitoba
Apr 30, 2018 BTH_II1242 Burkholderia thailandensis E264; ATCC 700388 New gene name: btaU. New product name: bactobolin hydroxylase BtaU. New PubMed ID: 19376863. New PubMed ID: 21615115. New PubMed ID: 20095633. New comment: Belongs to the bactobolin biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 AK34_RS06445 Burkholderia dolosa AU0158 New gene name: bceR. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. . New comment: Note that another gene (BCAM1493) for a two-component response regulator in B. cenocepacia J2315 was also assigned the name bceR at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4476. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0137 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssE2. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BCAL0408 Burkholderia cenocepacia J2315 New gene name: pacL. New product name: PacL. New product name synonym: putative 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase. New product name confidence: Class 2. New PubMed ID: 21296885. New PubMed ID: 18776009. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P3J4. Dustin Lavallee and Silvia Cardona, University of Manitoba
Apr 30, 2018 BTH_II1512 Burkholderia thailandensis E264; ATCC 700388 New gene name: btaI1. New product name: BtaI1. New PubMed ID: 19648250. New comment: Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BPSS1684 Burkholderia pseudomallei K96243 New gene name: bceR. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. . New comment: Note that another gene (BCAM1493) for a two-component response regulator in B. cenocepacia J2315 was also assigned the name bceR at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4476. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0138 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system-associated protein TagJ-2. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BP1026B_I0260 Burkholderia pseudomallei 1026b New gene name: pacL. New product name: PacL. New product name synonym: putative 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase. New product name confidence: Class 2. New PubMed ID: 21296885. New PubMed ID: 18776009. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P3J4. Geoff Winsor, Simon Fraser University. Transferred annotation from the B. cenocepacia annotation provided by D. Lavellee and S. Cardona.
Apr 30, 2018 BTH_II0804 Burkholderia thailandensis E264; ATCC 700388 New gene name: btaI3. New product name: BtaI3. New PubMed ID: 19648250. New comment: Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0695 Burkholderia thailandensis E264; ATCC 700388 New gene name: bceR. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. . New comment: Note that another gene (BCAM1493) for a two-component response regulator in B. cenocepacia J2315 was also assigned the name bceR at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4476. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0139 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system-associated protein TagK-2. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BPSL3041 Burkholderia pseudomallei K96243 New gene name: pacL. New product name: PacL. New product name synonym: putative 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase. New product name confidence: Class 2. New PubMed ID: 21296885. New PubMed ID: 18776009. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P3J4. Geoff Winsor, Simon Fraser University. Transferred annotation from the B. cenocepacia annotation provided by D. Lavellee and S. Cardona.
Apr 30, 2018 BTH_II1681 Burkholderia thailandensis E264; ATCC 700388 New gene name: thaA. New product name: ThaA. New PubMed ID: 29283242. New PubMed ID: 20853892. New comment: Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 bglu_2g08550 Burkholderia glumae BGR1 New gene name: bceR. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. . New comment: Note that another gene (BCAM1493) for a two-component response regulator in B. cenocepacia J2315 was also assigned the name bceR at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4476. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0140 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssH-2. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-2 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 I35_RS02045 Burkholderia cenocepacia H111 New gene name: pacL. New product name: PacL. New product name synonym: putative 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase. New product name confidence: Class 2. New PubMed ID: 21296885. New PubMed ID: 18776009. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P3J4. Geoff Winsor, Simon Fraser University. Transferred annotation from the B. cenocepacia annotation provided by D. Lavellee and S. Cardona.
Apr 30, 2018 BTH_II2087 Burkholderia thailandensis E264; ATCC 700388 New gene name: malR. New product name: MalR. New gene name synonym: btaR4. New product name confidence: Class 1. New PubMed ID: 29087175. New PubMed ID: 22765305. New comment: Belongs to the malleilactone biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 Bmul_4608 Burkholderia multivorans ATCC 17616 New gene name: bceR. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. . New comment: Note that another gene (BCAM1493) for a two-component response regulator in B. cenocepacia J2315 was also assigned the name bceR at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4476. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II1902 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssA-4. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-4 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BMAA0543 Burkholderia mallei ATCC 23344 New gene name: pacL. New product name: PacL. New product name synonym: putative 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase. New product name confidence: Class 2. New PubMed ID: 21296885. New PubMed ID: 18776009. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P3J4. Geoff Winsor, Simon Fraser University. Transferred annotation from the B. cenocepacia annotation provided by D. Lavellee and S. Cardona.
Apr 30, 2018 BTH_II2088 Burkholderia thailandensis E264; ATCC 700388 New gene name: malA. New product name: polyketide synthase MalA. New product name confidence: Class 1. New PubMed ID: 29087175. New PubMed ID: 22765305. New comment: Belongs to the malleilactone biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BAMB_RS16960 Burkholderia ambifaria AMMD New gene name: bceR. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. . New comment: Note that another gene (BCAM1493) for a two-component response regulator in B. cenocepacia J2315 was also assigned the name bceR at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4476. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II1901 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssB-4. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-4 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BCEP18194_RS08230 Burkholderia lata 383 New gene name: pacL. New product name: PacL. New product name synonym: putative 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase. New product name confidence: Class 2. New PubMed ID: 21296885. New PubMed ID: 18776009. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P3J4. Geoff Winsor, Simon Fraser University. Transferred annotation from the B. cenocepacia annotation provided by D. Lavellee and S. Cardona.
Apr 30, 2018 BTH_II2090 Burkholderia thailandensis E264; ATCC 700388 New gene name: malC. New product name: MalC. New PubMed ID: 29087175. New PubMed ID: 22765305. New comment: Belongs to the malleilactone biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 I35_RS21115 Burkholderia cenocepacia H111 New gene name: bceR. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. . New comment: Note that another gene (BCAM1493) for a two-component response regulator in B. cenocepacia J2315 was also assigned the name bceR at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4476. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II1900 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssC-4. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-4 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_I2900 Burkholderia thailandensis E264; ATCC 700388 New gene name: pacL. New product name: PacL. New product name synonym: putative 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase. New product name confidence: Class 2. New PubMed ID: 21296885. New PubMed ID: 18776009. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P3J4. Geoff Winsor, Simon Fraser University. Transferred annotation from the B. cenocepacia annotation provided by D. Lavellee and S. Cardona.
Apr 30, 2018 BTH_II2091 Burkholderia thailandensis E264; ATCC 700388 New gene name: malD. New product name: MalD. New PubMed ID: 29087175. New PubMed ID: 22765305. New comment: Belongs to the malleilactone biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BCEP18194_RS33300 Burkholderia lata 383 New gene name: bceR. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Disruption of the bceQ and bceR genes, in B. cepacia IST408 (PMID:19948863) resulted in the abolishment of cepacian biosynthesis. . New comment: Note that another gene (BCAM1493) for a two-component response regulator in B. cenocepacia J2315 was also assigned the name bceR at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4476. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II1899 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssD-4. New product name synonym: hemolysin-coregulated protein Hcp-4. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-4 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BMAA0543 Burkholderia mallei ATCC 23344 New PubMed ID: 21296885. New PubMed ID: 18776009. Annotation transferred from: UniProtKB:Q5P3J4. Geoff Winsor, Simon Fraser University. Transferred annotation from the B. cenocepacia annotation provided by D. Lavellee and S. Cardona.
Apr 30, 2018 BTH_II2092 Burkholderia thailandensis E264; ATCC 700388 New gene name: malE. New product name: MalE. New PubMed ID: 29087175. New PubMed ID: 22765305. New comment: Belongs to the malleilactone biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BCAM1009 Burkholderia cenocepacia J2315 New gene name: bceS. New product name: acyltransferase BceS. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Note that another gene (BCAM1494) for a two-component sensor kinase in B. cenocepacia J2315 was also assigned the name bceS at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4477. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II1898 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssE-4. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-4 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 bglu_1g04490 Burkholderia glumae BGR1 New gene name: pacL. New product name: PacL. New product name synonym: putative 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase. New product name confidence: Class 2. New PubMed ID: 21296885. New PubMed ID: 18776009. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH. . Annotation transferred from: UniProtKB:Q5P3J4. Geoff Winsor, Simon Fraser University. Transferred annotation from the B. cenocepacia annotation provided by D. Lavellee and S. Cardona.
Apr 30, 2018 BTH_II2093 Burkholderia thailandensis E264; ATCC 700388 New gene name: malF. New product name: polyketide synthase MalF. New product name confidence: Class 1. New PubMed ID: 29087175. New PubMed ID: 22765305. New comment: Belongs to the malleilactone biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 AK34_RS06440 Burkholderia dolosa AU0158 New gene name: bceS. New product name: acyltransferase BceS. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Note that another gene (BCAM1494) for a two-component sensor kinase in B. cenocepacia J2315 was also assigned the name bceS at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4477. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II1897 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssF-4. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-4 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 AK34_RS25965 Burkholderia dolosa AU0158 New gene name: pacL. New product name: PacL. New product name synonym: putative 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase. New product name confidence: Class 2. New PubMed ID: 21296885. New PubMed ID: 18776009. New comment: in E coli, paaZ encodes a bifunctional protein consisting of an N-terminal NADP-dependent aldehyde dehydrogenase domain and a C-terminal MaoC-like (R)-specific enoyl-CoA hydratase domain. In Burkholderia genomes, a gene incorrectly annotated as paaZ (e.g WQ49_RS11500) encodes only one of the two domains found in E.coli paaZ (the domain with semialdehyde dehydrogenase activity) and so is renamed PacL (PMID:21296885) but was also referred to as PaaZ-ALDH in the manuscript. In the same study , a separate A. aromaticum, protein (UniProtKB:Q5P232) with the (R)-hydratase activity was annotated as Ech-Aa and the Burkholderia ortholog was annotated as PaaZ-ECH.. Annotation transferred from: UniProtKB:Q5P3J4. Geoff Winsor, Simon Fraser University. Transferred annotation from the B. cenocepacia annotation provided by D. Lavellee and S. Cardona.
Apr 30, 2018 BTH_II2094 Burkholderia thailandensis E264; ATCC 700388 New gene name: malG. New product name: MalG. New PubMed ID: 29087175. New PubMed ID: 22765305. New comment: Belongs to the malleilactone biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BPSS1683 Burkholderia pseudomallei K96243 New gene name: bceS. New product name: acyltransferase BceS. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Note that another gene (BCAM1494) for a two-component sensor kinase in B. cenocepacia J2315 was also assigned the name bceS at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4477. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II1896 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssG-4. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-4 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II2095 Burkholderia thailandensis E264; ATCC 700388 New gene name: malI. New product name: MalI. New PubMed ID: 29087175. New PubMed ID: 22765305. New comment: Belongs to the malleilactone biosynthetic gene cluster. New comment: Incorrect translation start site called at 2571743 during initial annotation. The site was changed to 2573204 based on alignment with B. pseudomallei K96243 BPSS0303. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II0697 Burkholderia thailandensis E264; ATCC 700388 New gene name: bceS. New product name: acyltransferase BceS. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Note that another gene (BCAM1494) for a two-component sensor kinase in B. cenocepacia J2315 was also assigned the name bceS at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4477. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II1895 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssH-4. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-4 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II2096 Burkholderia thailandensis E264; ATCC 700388 New gene name: malJ. New product name: MalJ. New PubMed ID: 29087175. New PubMed ID: 22765305. New comment: Belongs to the malleilactone biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 bglu_2g08560 Burkholderia glumae BGR1 New gene name: bceS. New product name: acyltransferase BceS. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Note that another gene (BCAM1494) for a two-component sensor kinase in B. cenocepacia J2315 was also assigned the name bceS at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4477. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II1894 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssI-4a. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-4 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II2097 Burkholderia thailandensis E264; ATCC 700388 New gene name: malK. New product name: MalK. New PubMed ID: 29087175. New PubMed ID: 22765305. New comment: Belongs to the malleilactone biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 Bmul_4607 Burkholderia multivorans ATCC 17616 New product name: acyltransferase BceS. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Note that another gene (BCAM1494) for a two-component sensor kinase in B. cenocepacia J2315 was also assigned the name bceS at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4477. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II1893 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system protein TssI-4b. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-4 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II2098 Burkholderia thailandensis E264; ATCC 700388 New gene name: malL. New product name: MalL. New PubMed ID: 29087175. New PubMed ID: 22765305. New comment: Belongs to the malleilactone biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BAMB_RS16965 Burkholderia ambifaria AMMD New gene name: bceS. New product name: acyltransferase BceS. New product name confidence: Class 2. New PubMed ID: 19948863. New comment: Note that another gene (BCAM1494) for a two-component sensor kinase in B. cenocepacia J2315 was also assigned the name bceS at a later date (PMID:25519693).. New comment: Member of the bce-II gene cluster.Annotation transferred from: BGD:Bcep1808_4477. Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II1892 Burkholderia thailandensis E264; ATCC 700388 New product name: type VI secretion system-associated protein TagAB-4. New product name confidence: Class 2. New PubMed ID: 17660433. New PubMed ID: 22007185. New PubMed ID: 17555434. New PubMed ID: 20865170. New comment: This gene is part of cluster known as the type VI secretion system gene cluster tss-4 based on naming convention used for B. pseudomallei described in PMID:17660433, however unlike B. pseudomallei, the numbers following the vgrG and hcp gene match the cluster number (PMID:20865170). Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
Apr 30, 2018 BTH_II2099 Burkholderia thailandensis E264; ATCC 700388 New gene name: malM. New product name: MalM. New PubMed ID: 29087175. New PubMed ID: 22765305. New comment: Belongs to the malleilactone biosynthetic gene cluster Literature review. Geoff Winsor, Brinkman Lab, Simon Fraser University, Canada
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