Burkholderia glumae BGR1, bglu_2g06430 (toxD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia glumae BGR1
GCF_000022645.2|latest
Locus Tag
bglu_2g06430
NCBI Locus TagBGLU_RS21070
Name
toxD
Synonym: TRP-2
Replicon chromosome 2
Genomic location 772445 - 773425 (+ strand)
CommentMember of the toxoflavin biosynthesis gene cluster.
CommentFurther details in Identification of Proteins Involved in Toxin Production by Pseudomonas glumae. published in Japanese Journal of Phytopathology 64(2):75-79,January 1998.

Cross-References

RefSeq WP_012733474.1
GI
Entrez 7904517
NCBI Locus Tag BGLU_RS21070
NCBI Old Locus Tag bglu_2g06430
RefSeq WP_012733474.1,GeneID

Product

Feature Type CDS
Coding Frame 1
Product Name
ToxD
Product Name Confidence: Class 1
Synonyms serine/threonine kinase
Evidence for Translation
Charge (pH 7) -8.64
Kyte-Doolittle Hydrophobicity Value -0.216
Molecular Weight (kDa) 35505.6
Isoelectric Point (pI) 5.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 280 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG018051 (340 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: bglu_2g06430
Search term: toxD
Search term: ToxD

Human Homologs

References

Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
Fenwick MK, Philmus B, Begley TP, Ealick SE
Biochemistry 2016 May 17;55(19):2748-59
PubMed ID: 27070241