Burkholderia glumae BGR1, bglu_2g06420 (toxC)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia glumae BGR1
GCF_000022645.2|latest |
| Locus Tag |
bglu_2g06420
|
| NCBI Locus Tag | BGLU_RS21065 |
| Name |
toxC
|
| Replicon | chromosome 2 |
| Genomic location | 770646 - 772337 (+ strand) |
| Comment | Member of the toxoflavin biosynthesis gene cluster |
Cross-References
| RefSeq | WP_012733473.1 |
| GI | |
| Entrez | 7904516 |
| NCBI Locus Tag | BGLU_RS21065 |
| NCBI Old Locus Tag | bglu_2g06420 |
| RefSeq | WP_012733473.1,GeneID |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
ToxC
|
| Synonyms |
WD-repeat-containing protein |
| Evidence for Translation | |
| Charge (pH 7) | -9.87 |
| Kyte-Doolittle Hydrophobicity Value | -0.218 |
| Molecular Weight (kDa) | 61556.3 |
| Isoelectric Point (pI) | 6.20 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Pathogen Association Analysis
| Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 133 genera
|
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG018053 (348 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: bglu_2g06420
Search term: toxC
Search term: ToxC
|
Human Homologs
References
|
Burkholderia glumae ToxA Is a Dual-Specificity Methyltransferase That Catalyzes the Last Two Steps of Toxoflavin Biosynthesis.
Fenwick MK, Philmus B, Begley TP, Ealick SE
Biochemistry 2016 May 17;55(19):2748-59
PubMed ID: 27070241
|