Burkholderia cenocepacia J2315, BCAM2231 (pchR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2231
NCBI Locus TagQU43_RS65520
Name
pchR
Replicon chromosome 2
Genomic location 2501193 - 2502311 (- strand)

Cross-References

RefSeq YP_002234829.1
GI 206564066
Entrez 6930590
GI 206564066
NCBI Locus Tag QU43_RS65520
NCBI Old Locus Tag BCAM2231
RefSeq YP_002234829.1
UniProtKB Acc B4EGG2
UniProtKB ID B4EGG2_BURCJ

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator PchR
Synonyms
Evidence for Translation
Charge (pH 7) 11.55
Kyte-Doolittle Hydrophobicity Value -0.141
Molecular Weight (kDa) 40407.0
Isoelectric Point (pI) 8.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 315 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006695 (377 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2231
Search term: pchR

Human Homologs

References

Dihydroaeruginoic acid synthetase and pyochelin synthetase, products of the pchEF genes, are induced by extracellular pyochelin in Pseudomonas aeruginosa.
Reimmann C, Serino L, Beyeler M, Haas D
Microbiology 1998 Nov;144 ( Pt 11):3135-48
PubMed ID: 9846750
Erratum in: J Bacteriol. 2009 Apr;191(8):2907.
The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients.
J Bacteriol. 2009 Jan;191(1):261-77.
PubMed ID: 18931103