Burkholderia cenocepacia J2315, BCAM2224 (fptA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
Locus Tag
BCAM2224
NCBI Locus TagQU43_RS65490
Name
fptA
Replicon chromosome 2
Genomic location 2484354 - 2486537 (- strand)

Cross-References

RefSeq WP_006486761.1
GI 206564061
Entrez 6929810
GI 206564061
INSDC CAR56082.1
NCBI Locus Tag QU43_RS65490
NCBI Old Locus Tag BCAM2224
RefSeq WP_006486761.1,GeneID
UniParc UPI00017B9FE0
UniProtKB Acc B4EGF6
UniProtKB ID B4EGF6_BURCJ
UniRef100 UniRef100_U1ZI91
UniRef50 UniRef50_P42512
UniRef90 UniRef90_U1ZI91

Product

Feature Type CDS
Coding Frame 1
Product Name
putative pyochelin receptor protein FptA
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) 7.07
Kyte-Doolittle Hydrophobicity Value -0.292
Molecular Weight (kDa) 79332.1
Isoelectric Point (pI) 8.84

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 258 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006690 (388 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2224
Search term: fptA

References

Dihydroaeruginoic acid synthetase and pyochelin synthetase, products of the pchEF genes, are induced by extracellular pyochelin in Pseudomonas aeruginosa.
Reimmann C, Serino L, Beyeler M, Haas D.
Microbiology. 1998 Nov;144 ( Pt 11):3135-48.
PubMed ID: 9846750
Erratum in: J Bacteriol. 2009 Apr;191(8):2907.
The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients.
J Bacteriol. 2009 Jan;191(1):261-77.
PubMed ID: 18931103
Importance of the ornibactin and pyochelin siderophore transport systems in Burkholderia cenocepacia lung infections.
Visser MB(1), Majumdar S, Hani E, Sokol PA.
Infect Immun. 2004 May;72(5):2850-7.
PubMed ID: 15102796