Burkholderia cenocepacia J2315, BCAM2045 (bcscU)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM2045
NCBI Locus TagQU43_RS64585
Name
bcscU
Replicon chromosome 2
Genomic location 2277231 - 2278262 (- strand)

Cross-References

RefSeq WP_006489707.1
GI 206563886
Entrez 6929666
GI 206563886
INSDC CAR55904.1
NCBI Locus Tag QU43_RS64585
NCBI Old Locus Tag BCAM2045
RefSeq WP_006489707.1,GeneID
UniParc UPI000000545F
UniProtKB Acc B4EN88
UniProtKB ID B4EN88_BURCJ
UniRef100 UniRef100_Q8VP12
UniRef50 UniRef50_A9AP23
UniRef90 UniRef90_A9AP23

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system protein
Synonyms
Evidence for Translation
Charge (pH 7) 9.17
Kyte-Doolittle Hydrophobicity Value 0.253
Molecular Weight (kDa) 37322.3
Isoelectric Point (pI) 10.17

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 322 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003793 (264 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM2045
Search term: bcscU

Human Homologs

References

A putative type III secretion gene cluster is widely distributed in the Burkholderia cepacia complex but absent from genomovar I.
Parsons YN, Glendinning KJ, Thornton V, Hales BA, Hart CA, Winstanley C
FEMS Microbiol Lett 2001 Sep 11;203(1):103-8
PubMed ID: 11557147
Sequence divergence in type III secretion gene clusters of the Burkholderia cepacia complex.
Glendinning KJ, Parsons YN, Duangsonk K, Hales BA, Humphreys D, Hart CA, Winstanley C
FEMS Microbiol Lett 2004 Jun 15;235(2):229-35
PubMed ID: 15183868