Burkholderia cenocepacia J2315, BCAM1868 (cepR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
Locus Tag
BCAM1868
NCBI Locus TagQU43_RS63740
Name
cepR
Replicon chromosome 2
Genomic location 2086737 - 2087456 (- strand)

Cross-References

RefSeq WP_006483948.1
GI 206563716
Entrez 6929502
GI 206563716
INSDC CAR55726.1
NCBI Locus Tag QU43_RS63740
NCBI Old Locus Tag BCAM1868
RefSeq WP_006483948.1,GeneID
UniParc UPI00017BA09B
UniProtKB Acc B4EMD0
UniProtKB ID B4EMD0_BURCJ
UniRef100 UniRef100_B4EMD0
UniRef50 UniRef50_P58590
UniRef90 UniRef90_B4EMD0

Product

Feature Type CDS
Coding Frame 1
Product Name
N-acylhomoserine lactone dependent regulatory protein CepR
Product Name Confidence: Class 1
Synonyms transcriptional regulator CepR
Evidence for Translation
Charge (pH 7) -3.20
Kyte-Doolittle Hydrophobicity Value -0.054
Molecular Weight (kDa) 26606.1
Isoelectric Point (pI) 5.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 369 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003718 (1367 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM1868
Search term: cepR

References

Distribution of quorum-sensing genes in the Burkholderia cepacia complex.
Lutter E, Lewenza S, Dennis JJ, Visser MB, Sokol PA.
Infect Immun. 2001 Jul;69(7):4661-6.
PubMed ID: 11402012
Identification of functions linking quorum sensing with biofilm formation in Burkholderia cenocepacia H111.
Inhülsen S, Aguilar C, Schmid N, Suppiger A, Riedel K, Eberl L.
Microbiologyopen. 2012 Jun;1(2):225-42.
PubMed ID: 22950027
The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility.
Huber B, Riedel K, Hentzer M, Heydorn A, Gotschlich A, Givskov M, Molin S, Eberl L.
Microbiology. 2001 Sep;147(Pt 9):2517-28.
PubMed ID: 11535791