Burkholderia cenocepacia J2315, BCAM1661 (ecfH)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAM1661
Name	ecfH
Replicon	chromosome 2
Genomic location	1845561 - 1846346 (- strand)

Cross-References

RefSeq	YP_002234272.1
GI	206563509
Entrez	6929301
GI	206563509
INSDC	CAR55516.1
RefSeq	YP_002234272.1
UniParc	UPI00017BA16F
UniProtKB Acc	B4EKR0
UniProtKB ID	B4EKR0_BURCJ
UniRef100	UniRef100_B4EKR0
UniRef50	UniRef50_B4EKR0
UniRef90	UniRef90_B4EKR0

Product

Feature Type	CDS
Coding Frame	1
Product Name	RNA polymerase sigma factor Product Name Confidence: Class 1
Synonyms	sigma factor 70 EcfH
Evidence for Translation
Charge (pH 7)	2.67
Kyte-Doolittle Hydrophobicity Value	-0.763
Molecular Weight (kDa)	29166.3
Isoelectric Point (pI)	8.75

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown Class 3 20472543 Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 474 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG003549 (228 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAM1661 Search term: ecfH Search term: RNA polymerase sigma factor

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability. Menard A, de Los Santos PE, Graindorge A, Cournoyer B BMC Genomics 2007 Sep 4;8:308 PubMed ID: 17784948