Burkholderia cenocepacia J2315, BCAM0918 (sigE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAM0918
NCBI Locus TagQU43_RS58960
Name
sigE
Replicon chromosome 2
Genomic location 1009947 - 1011812 (+ strand)

Cross-References

RefSeq YP_002233536.1
GI 206562773
Entrez 6928653
GI 206562773
INSDC CAR54775.1
NCBI Locus Tag QU43_RS58960
NCBI Old Locus Tag BCAM0918
RefSeq YP_002233536.1
UniParc UPI00017B9ACC
UniProtKB Acc B4EN36
UniProtKB ID B4EN36_BURCJ
UniRef100 UniRef100_B4EN36
UniRef50 UniRef50_Q0K867
UniRef90 UniRef90_Q9ZFR4

Product

Feature Type CDS
Coding Frame 1
Product Name
RNA polymerase sigma factor RpoD
Product Name Confidence: Class 1
Synonyms sigma factor 70 sigE
Evidence for Translation
Charge (pH 7) -35.83
Kyte-Doolittle Hydrophobicity Value -0.532
Molecular Weight (kDa) 70372.8
Isoelectric Point (pI) 4.54

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 591 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003025 (663 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAM0918
Search term: sigE

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability.
Menard A, de Los Santos PE, Graindorge A, Cournoyer B
BMC Genomics 2007 Sep 4;8:308
PubMed ID: 17784948