Strain |
Burkholderia cenocepacia J2315
GCF_000009485.1|latest |
Locus Tag |
BCAM0186
|
NCBI Locus Tag | QU43_RS55350 |
Name |
bclA
|
Replicon | chromosome 2 |
Genomic location | 216624 - 217013 (- strand) |
RefSeq | WP_006479996.1 |
GI | 206562056 |
Entrez | 6927982 |
GI | 206562056 |
INSDC | CAR54044.1 |
NCBI Locus Tag | QU43_RS55350 |
NCBI Old Locus Tag | BCAM0186 |
RefSeq | WP_006479996.1,GeneID |
UniParc | UPI000052D833 |
UniProtKB Acc | B4EH87 |
UniProtKB ID | B4EH87_BURCJ |
UniRef100 | UniRef100_B1K8B3 |
UniRef50 | UniRef50_B1YYC5 |
UniRef90 | UniRef90_B1YYC5 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
lectin
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -3.29 |
Kyte-Doolittle Hydrophobicity Value | -0.510 |
Molecular Weight (kDa) | 13895.2 |
Isoelectric Point (pI) | 5.12 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
2WRA | SUGAR BINDING PROTEIN | 09/01/09 | BclA lectin from Burkholderia cenocepacia complexed with aMan1(aMan1- 6)-3Man trisaccharide | BURKHOLDERIA CENOCEPACIA | 1.1 | X-RAY DIFFRACTION | 100.0 |
2WR9 | SUGAR BINDING PROTEIN | 09/01/09 | CRYSTAL STRUCTURE OF BURKHOLDERIA CENOCEPACIA LECTIN (BCLA) COMPLEXED WITH AMAN1-3MAN DISACCHARIDE | BURKHOLDERIA CENOCEPACIA | 1.75 | X-RAY DIFFRACTION | 100.0 |
2VNV | SUGAR BINDING PROTEIN | 02/07/08 | Crystal structure of BclA lectin from burkholderia cenocepacia in complex with alpha-methyl-mannoside at 1.7 Angstrom resolution | BURKHOLDERIA CENOCEPACIA | 1.7 | X-RAY DIFFRACTION | 100.0 |
4AOC | HYDROLASE | 03/26/12 | crystal structure of BC2L-A Lectin from Burkolderia cenocepacia in complex with methyl-heptoside | BURKHOLDERIA CENOCEPACIA | 2.7 | X-RAY DIFFRACTION | 100.0 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 6 genera
|
Burkholderia Ortholog Group |
BG005619 (149 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BCAM0186
Search term: bclA
Search term: lectin
|
Structural basis for mannose recognition by a lectin from opportunistic bacteria Burkholderia cenocepacia.
Lameignere E, Malinovská L, Sláviková M, Duchaud E, Mitchell EP, Varrot A, Sedo O, Imberty A, Wimmerová M
Biochem J 2008 Apr 15;411(2):307-18
PubMed ID: 18215132
|
Identification of functions linking quorum sensing with biofilm formation in Burkholderia cenocepacia H111.
Inhülsen S, Aguilar C, Schmid N, Suppiger A, Riedel K, Eberl L
Microbiologyopen 2012 Jun;1(2):225-42
PubMed ID: 22950027
|