Burkholderia cenocepacia J2315, BCAL3310 (bcnB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL3310
NCBI Locus TagQU43_RS53250
Name
bcnB
Replicon chromosome 1
Genomic location 3628545 - 3629126 (- strand)

Cross-References

RefSeq WP_006476873.1
GI 206561648
Entrez 6933135
GI 206561648
INSDC CAR53633.1
NCBI Locus Tag QU43_RS53250
NCBI Old Locus Tag BCAL3310
RefSeq WP_006476873.1,GeneID
UniParc UPI000052EF4A
UniProtKB Acc B4EE31
UniProtKB ID B4EE31_BURCJ
UniRef100 UniRef100_B1JVY1
UniRef50 UniRef50_Q1LJ50
UniRef90 UniRef90_Q39JG1

Product

Feature Type CDS
Coding Frame 1
Product Name
BcnB
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 2.61
Kyte-Doolittle Hydrophobicity Value -0.208
Molecular Weight (kDa) 20988.7
Isoelectric Point (pI) 8.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5IXG UNKNOWN FUNCTION 03/23/16 Crystal Structure of Burkholderia cenocepacia BcnB BURKHOLDERIA CENOCEPACIA PC184 1.6 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 302 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000590 (654 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL3310
Search term: bcnB
Search term: BcnB

Human Homologs

References

Antibiotic Capture by Bacterial Lipocalins Uncovers an Extracellular Mechanism of Intrinsic Antibiotic Resistance.
El-Halfawy OM, Klett J, Ingram RJ, Loutet SA, Murphy ME, Martín-Santamaría S, Valvano MA
mBio 2017 Mar 14;8(2)
PubMed ID: 28292982