Burkholderia cenocepacia J2315, BCAL3135 (rmlB)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL3135
NCBI Locus Tag	QU43_RS52395
Name	rmlB
Replicon	chromosome 1
Genomic location	3426181 - 3427242 (- strand)

Cross-References

RefSeq	WP_006485109.1
GI	206561479
Entrez	6934045
GI	206561479
INSDC	CAR53458.1
NCBI Locus Tag	QU43_RS52395
NCBI Old Locus Tag	BCAL3135
RefSeq	WP_006485109.1,GeneID
UniParc	UPI00017B9996
UniProtKB Acc	B4ECS6
UniProtKB ID	B4ECS6_BURCJ
UniRef100	UniRef100_B4ECS6
UniRef50	UniRef50_P55294
UniRef90	UniRef90_B4ECS6

Product

Feature Type	CDS
Coding Frame	1
Product Name	dTDP-D-glucose 4,6-dehydratase Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7)	-3.24
Kyte-Doolittle Hydrophobicity Value	-0.429
Molecular Weight (kDa)	39545.0
Isoelectric Point (pI)	6.51

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 643 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000730 (655 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL3135 Search term: rmlB Search term: dTDP-D-glucose 4,6-dehydratase

Human Homologs

References

A new route to dTDP-6-deoxy-l-talose and dTDP-L-rhamnose: dTDP-L-rhamnose 4-epimerase in Burkholderia thailandensis. Yoo HG, Kwon SY, Karki S, Kwon HJ Bioorg Med Chem Lett 2011 Jul 1;21(13):3914-7 PubMed ID: 21640586