Burkholderia cenocepacia J2315, BCAL2946 (udg)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL2946
NCBI Locus Tag	QU43_RS51375
Name	udg
Replicon	chromosome 1
Genomic location	3224205 - 3225605 (- strand)

Cross-References

RefSeq	WP_006486856.1
GI	206561281
Entrez	6933725
GI	206561281
INSDC	CAR53247.1
NCBI Locus Tag	QU43_RS51375
NCBI Old Locus Tag	BCAL2946
RefSeq	WP_006486856.1,GeneID
UniParc	UPI00017B9733
UniProtKB Acc	B4EB36
UniProtKB ID	B4EB36_BURCJ
UniRef100	UniRef100_G7HIB2
UniRef50	UniRef50_Q72AT3
UniRef90	UniRef90_B9BSF4

Product

Feature Type	CDS
Coding Frame	1
Product Name	putative UDP-glucose dehydrogenase Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7)	-10.90
Kyte-Doolittle Hydrophobicity Value	-0.117
Molecular Weight (kDa)	50895.3
Isoelectric Point (pI)	5.16

Subcellular localization

Individual Mappings	Localization Confidence PMID Unknown (This protein may have multiple localization sites) Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 589 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG000893 (1284 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL2946 Search term: udg Search term: putative UDP-glucose dehydrogenase

Human Homologs

References

A complete lipopolysaccharide inner core oligosaccharide is required for resistance of Burkholderia cenocepacia to antimicrobial peptides and bacterial survival in vivo. Loutet SA, Flannagan RS, Kooi C, Sokol PA, Valvano MA J Bacteriol 2006 Mar;188(6):2073-80 PubMed ID: 16513737

Contributions of two UDP-glucose dehydrogenases to viability and polymyxin B resistance of Burkholderia cenocepacia. Loutet SA, Bartholdson SJ, Govan JRW, Campopiano DJ, Valvano MA Microbiology 2009 Jun;155(Pt 6):2029-2039 PubMed ID: 19383677