Burkholderia cenocepacia J2315, BCAL2462 (ecfE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Burkholderia cenocepacia J2315
GCF_000009485.1|latest
Locus Tag
BCAL2462
NCBI Locus TagQU43_RS48985
Name
ecfE
Replicon chromosome 1
Genomic location 2727696 - 2728250 (- strand)

Cross-References

RefSeq WP_006497139.1
GI 206560821
Entrez 6932524
GI 206560821
INSDC CAR52763.1
NCBI Locus Tag QU43_RS48985
NCBI Old Locus Tag BCAL2462
RefSeq WP_006497139.1,GeneID
UniParc UPI00017B992C
UniProtKB Acc B4E728
UniProtKB ID B4E728_BURCJ
UniRef100 UniRef100_U1Z9N2
UniRef50 UniRef50_D8J0K5
UniRef90 UniRef90_V4ZU44

Product

Feature Type CDS
Coding Frame 1
Product Name
putative RNA polymerase sigma factor
Product Name Confidence: Class 1
Synonyms sigma factor 70 EcfE
Evidence for Translation
Charge (pH 7) -6.03
Kyte-Doolittle Hydrophobicity Value -0.519
Molecular Weight (kDa) 21262.8
Isoelectric Point (pI) 4.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 394 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG006145 (148 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BCAL2462
Search term: ecfE

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability.
Menard A, de Los Santos PE, Graindorge A, Cournoyer B
BMC Genomics 2007 Sep 4;8:308
PubMed ID: 17784948