Burkholderia cenocepacia J2315, BCAL2079 (lpxA)

Gene Feature Overview

Strain	Burkholderia cenocepacia J2315 GCF_000009485.1|latest
Locus Tag	BCAL2079
NCBI Locus Tag	QU43_RS46955
Name	lpxA
Replicon	chromosome 1
Genomic location	2286683 - 2287471 (- strand)

Cross-References

RefSeq	WP_006483825.1
GI	206560441
Entrez	6932240
GI	206560441
INSDC	CAR52379.1
NCBI Locus Tag	QU43_RS46955
NCBI Old Locus Tag	BCAL2079
RefSeq	WP_006483825.1,GeneID
UniParc	UPI00017B94B2
UniProtKB Acc	B4ECL9
UniProtKB ID	LPXA_BURCJ
UniRef100	UniRef100_B4ECL9
UniRef50	UniRef50_P32201
UniRef90	UniRef90_A4JF63

Product

Feature Type	CDS
Coding Frame	1
Product Name	UDP-N-acetylglucosamine acyltransferase Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7)	-2.15
Kyte-Doolittle Hydrophobicity Value	-0.062
Molecular Weight (kDa)	27813.3
Isoelectric Point (pI)	6.65

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 421 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group	BG001897 (654 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: BCAL2079 Search term: lpxA Search term: UDP-N-acetylglucosamine acyltransferase

Human Homologs

References

Complete structural characterization of the lipid A fraction of a clinical strain of B. cepacia genomovar I lipopolysaccharide. Silipo A, Molinaro A, Cescutti P, Bedini E, Rizzo R, Parrilli M, Lanzetta R Glycobiology 2005 May;15(5):561-70 PubMed ID: 15610978