Burkholderia pseudomallei 668, BURPS668_A2160 (bprA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia pseudomallei 668
GCF_000015905.1|latest
Locus Tag
BURPS668_A2160
NCBI Locus TagBURPS668_RS25890
Name
bprA
Replicon chromosome II
Genomic location 2097516 - 2097806 (- strand)

Cross-References

RefSeq WP_004187356.1
GI 126444061
Entrez 4886928
GI 126444061
INSDC ABN87057.1
NCBI Locus Tag BURPS668_RS25890
NCBI Old Locus Tag BURPS668_A2160
RefSeq WP_004187356.1
UniParc UPI000043BD1C
UniProtKB Acc A3NLD3
UniProtKB ID A3NLD3_BURP6
UniRef100 UniRef100_A3MCH0
UniRef50 UniRef50_B1Z6M2
UniRef90 UniRef90_A3MCH0

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA-binding protein BprA
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 6.47
Kyte-Doolittle Hydrophobicity Value -0.896
Molecular Weight (kDa) 10910.2
Isoelectric Point (pI) 10.44

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 40 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019831 (366 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BURPS668_A2160
Search term: bprA

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592