Burkholderia mallei ATCC 23344, BMAA1631 (sctU)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia mallei ATCC 23344
GCF_000011705.1|latest
Locus Tag
BMAA1631
Name
sctU
Replicon chromosome 2
Genomic location 1769840 - 1770922 (- strand)
CommentThis gene is part of the type III secretion system T3SS-2 locus found in B. malllei.

Cross-References

RefSeq YP_106206.1
GI 53716421
NCBI Locus Tag BMAA1631
RefSeq YP_106206.1,GeneID

Product

Feature Type CDS
Coding Frame 1
Product Name
autoprotease, early/middle substrate switch SctU (T3SS-2)
Product Name Confidence: Class 2
Synonyms type III secretion system protein HrcU
Evidence for Translation
Charge (pH 7) 13.87
Kyte-Doolittle Hydrophobicity Value 0.186
Molecular Weight (kDa) 38922.3
Isoelectric Point (pI) 10.36

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG017459 (457 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMAA1631
Search term: sctU

Human Homologs

References

Type III secretion system cluster 3 is required for maximal virulence of Burkholderia pseudomallei in a hamster infection model.
Warawa J, Woods DE
FEMS Microbiol Lett 2005 Jan 1;242(1):101-8
PubMed ID: 15621426
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152