Burkholderia mallei ATCC 23344, BMAA1536 (spaP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia mallei ATCC 23344
GCF_000011705.1|latest
Locus Tag
BMAA1536
Name
spaP
Synonym: sctR
Replicon chromosome 2
Genomic location 1664789 - 1665469 (- strand)
CommentThis gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus.

Cross-References

RefSeq YP_106126.1
GI 53716462
NCBI Locus Tag BMAA1536
RefSeq YP_106126.1,GeneID

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion system inner membrane export apparatus protein BsaW (T3SS-3)
Product Name Confidence: Class 2
Synonyms surface presentation of antigens protein SpaP
Evidence for Translation
Charge (pH 7) -5.59
Kyte-Doolittle Hydrophobicity Value 0.667
Molecular Weight (kDa) 24769.0
Isoelectric Point (pI) 4.58

Subcellular localization

Individual Mappings
Localization Confidence PMID
Flagellar
Note: This is based on PSORTb V3.0 secondary localization prediction
Class 3
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019840 (324 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMAA1536
Search term: spaP

Human Homologs

References

Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152