Burkholderia mallei ATCC 23344, BMAA1525 (bapB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia mallei ATCC 23344
GCF_000011705.1|latest
Locus Tag
BMAA1525
Name
bapB
Replicon chromosome 2
Genomic location 1654157 - 1654438 (- strand)
CommentThis gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus.

Cross-References

RefSeq YP_106116.1
GI 53716479
NCBI Locus Tag BMAA1525
RefSeq YP_106116.1,GeneID

Product

Feature Type CDS
Coding Frame 1
Product Name
BapB (T3SS-3)
Product Name Confidence: Class 2
Synonyms BapB protein
Evidence for Translation
Charge (pH 7) -7.77
Kyte-Doolittle Hydrophobicity Value 0.299
Molecular Weight (kDa) 9622.8
Isoelectric Point (pI) 4.07

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019827 (317 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMAA1525
Search term: bapB
Search term: BapB (T3SS-3)

Human Homologs

References

The Burkholderia pseudomallei Proteins BapA and BapC Are Secreted TTSS3 Effectors and BapB Levels Modulate Expression of BopE.
Treerat P, Alwis P, D'Cruze T, Cullinane M, Vadivelu J, Devenish RJ, Prescott M, Adler B, Boyce JD
PLoS One 2015;10(12):e0143916
PubMed ID: 26624293
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152