Burkholderia mallei ATCC 23344, BMAA1524 (bapC)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Burkholderia mallei ATCC 23344
GCF_000011705.1|latest |
| Locus Tag |
BMAA1524
|
| Name |
bapC
|
| Replicon | chromosome 2 |
| Genomic location | 1653597 - 1654160 (- strand) |
| Comment | This gene is part of the Burkholderia mallei type III secretion system T3SS-3 gene locus. |
Cross-References
| RefSeq | YP_106115.1 |
| GI | 53716480 |
| NCBI Locus Tag | BMAA1524 |
| RefSeq | YP_106115.1,GeneID |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
type III secretion system effector protein BapC (T3SS-3)
|
| Synonyms |
BapC protein |
| Evidence for Translation | |
| Charge (pH 7) | 9.40 |
| Kyte-Doolittle Hydrophobicity Value | -0.239 |
| Molecular Weight (kDa) | 20199.5 |
| Isoelectric Point (pI) | 10.32 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Virulence Evidence
| Source 1 | |
| Database | VFDB : VF0428 |
| Category | T3SS-3 |
| Evidence |
ECO:0000250
sequence similarity evidence used in manual assertion
|
| Host Organism | |
| Notes | |
| Annotation transferred from | Burkholderia pseudomallei K96243 |
| Reference | 17984080 |
Pathogen Association Analysis
| Results | Analysis not done |
Orthologs/Comparative Genomics
| Burkholderia Ortholog Group |
BG019826 (317 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: BMAA1524
Search term: bapC
|
Human Homologs
References
|
The Burkholderia pseudomallei Proteins BapA and BapC Are Secreted TTSS3 Effectors and BapB Levels Modulate Expression of BopE.
Treerat P, Alwis P, D'Cruze T, Cullinane M, Vadivelu J, Devenish RJ, Prescott M, Adler B, Boyce JD
PLoS One 2015;10(12):e0143916
PubMed ID: 26624293
|
|
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
|