Burkholderia mallei NCTC 10247, BMA10247_A0768 (bprD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia mallei NCTC 10247
GCF_000015625.1|latest
Locus Tag
BMA10247_A0768
NCBI Locus TagBMA10247_RS03150
Name
bprD
Replicon chromosome II
Genomic location 709779 - 710222 (+ strand)

Cross-References

RefSeq WP_004203128.1
GI 126447365
Entrez 4889691
GI 126447365
INSDC ABO03331.1
NCBI Locus Tag BMA10247_RS03150
NCBI Old Locus Tag BMA10247_A0768
RefSeq WP_004203128.1
UniParc UPI000043BD13
UniProtKB Acc A3MCI2
UniProtKB ID A3MCI2_BURM7
UniRef100 UniRef100_A0A097XM68
UniRef50 UniRef50_Q2T700
UniRef90 UniRef90_Q2T700

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 16.92
Kyte-Doolittle Hydrophobicity Value -0.686
Molecular Weight (kDa) 16672.2
Isoelectric Point (pI) 11.42

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Pathogenic
Found only in pathogenic strains
Hits to this gene were found in one genus

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019819 (316 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMA10247_A0768
Search term: bprD

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592