Burkholderia mallei NCTC 10247, BMA10247_A0754 (bipC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia mallei NCTC 10247
GCF_000015625.1|latest
Locus Tag
BMA10247_A0754
NCBI Locus TagBMA10247_RS03095
Name
bipC
Replicon chromosome II
Genomic location 698210 - 699475 (+ strand)

Cross-References

RefSeq YP_001077955.1
GI 126446226
Entrez 4890435
GI 126446226
INSDC ABO02192.1
NCBI Locus Tag BMA10247_RS03095
NCBI Old Locus Tag BMA10247_A0754
RefSeq YP_001077955.1
UniParc UPI000043BD1D
UniProtKB Acc A3MCG9
UniProtKB ID BIPC_BURM7
UniRef100 UniRef100_A3MCG9
UniRef50 UniRef50_A3MCG9
UniRef90 UniRef90_A3MCG9

Product

Feature Type CDS
Coding Frame 1
Product Name
type III secretion target BipC
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 5.63
Kyte-Doolittle Hydrophobicity Value -0.586
Molecular Weight (kDa) 44609.5
Isoelectric Point (pI) 9.50

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Host Associated
Note: This is based on PSORTb V3.0 secondary localization prediction
 Class 3
Unknown (This protein may have multiple localization sites) Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Pathogenic
Found only in pathogenic strains
Hits to this gene were found in 2 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019833 (317 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BMA10247_A0754
Search term: bipC

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592