Burkholderia cenocepacia MC0-3, Bcenmc03_1085 (ecfA1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia cenocepacia MC0-3
GCF_000019505.1|latest
Locus Tag
Bcenmc03_1085
NCBI Locus TagBCENMC03_RS05530
Name
ecfA1
Replicon chromosome 1
Genomic location 1190180 - 1190779 (+ strand)

Cross-References

RefSeq WP_006490873.1
GI 170732437
Entrez 6122765
GI 170732437
INSDC ACA90262.1
NCBI Locus Tag BCENMC03_RS05530
NCBI Old Locus Tag Bcenmc03_1085
RefSeq WP_006490873.1
UniParc UPI0000376467
UniProtKB Acc B1JYA6
UniProtKB ID B1JYA6_BURCC
UniRef100 UniRef100_A0A071MHT6
UniRef50 UniRef50_D0ZSY9
UniRef90 UniRef90_Q2SXU1

Product

Feature Type CDS
Coding Frame 1
Product Name
RNA polymerase sigma factor RpoE
Product Name Confidence: Class 1
Synonyms sigma factor 70 EcfA1
Evidence for Translation
Charge (pH 7) -2.79
Kyte-Doolittle Hydrophobicity Value -0.372
Molecular Weight (kDa) 22593.5
Isoelectric Point (pI) 5.21

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 496 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000968 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: Bcenmc03_1085
Search term: ecfA1

Human Homologs

References

Architecture of Burkholderia cepacia complex sigma70 gene family: evidence of alternative primary and clade-specific factors, and genomic instability.
Menard A, de Los Santos PE, Graindorge A, Cournoyer B
BMC Genomics 2007 Sep 4;8:308
PubMed ID: 17784948