Burkholderia thailandensis E264 ATCC 700388, BTH_I1158

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest
Locus Tag
BTH_I1158
NCBI Locus TagBTH_RS18115
Name
Replicon chromosome I
Genomic location 1304723 - 1305661 (- strand)
Transposon Mutants 3 transposon mutants in E264 ATCC 700388

Cross-References

RefSeq YP_441705.1
GI 83720649
Entrez 3849972
GI 83720649
INSDC AIP24308.1
NCBI Locus Tag BTH_RS18115
NCBI Old Locus Tag BTH_I1158
RefSeq WP_009888955.1
UniParc UPI00006683B3
UniProtKB Acc Q2SZE4
UniProtKB ID Q2SZE4_BURTA
UniRef100 UniRef100_Q2SZE4
UniRef50 UniRef50_Q2SZE4
UniRef90 UniRef90_Q2SZE4

Product

Feature Type CDS
Coding Frame 1
Product Name
ribokinase
Product Name Confidence: Class 2
Synonyms Nucleoside kinase
Evidence for Translation
Charge (pH 7) -8.72
Kyte-Doolittle Hydrophobicity Value -0.108
Molecular Weight (kDa) 34012.3
Isoelectric Point (pI) 5.35

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3B1N TRANSFERASE 07/05/11 Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in complex with ADP-mizoribine BURKHOLDERIA THAILANDENSIS 1.55 X-RAY DIFFRACTION 100.0
3B1O TRANSFERASE 07/05/11 Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in ligand-free form BURKHOLDERIA THAILANDENSIS 2.1 X-RAY DIFFRACTION 100.0
3B1P TRANSFERASE 07/05/11 Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in complex with ADP-inosine BURKHOLDERIA THAILANDENSIS 1.7 X-RAY DIFFRACTION 100.0
3B1Q TRANSFERASE 07/05/11 Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in complex with inosine BURKHOLDERIA THAILANDENSIS 1.7 X-RAY DIFFRACTION 100.0
3B1R TRANSFERASE 07/05/11 Structure of Burkholderia thailandensis nucleoside kinase (BthNK) in complex with AMP-Mg-AMP BURKHOLDERIA THAILANDENSIS 2.0 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 398 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG000487 (655 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_I1158
Search term: ribokinase

Human Homologs

References

No references are associated with this feature.