Burkholderia thailandensis E264 ATCC 700388, BTH_II0849 (bopA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest
Locus Tag
BTH_II0849
NCBI Locus TagBTH_RS04410
Name
bopA
Replicon chromosome II
Genomic location 991240 - 992778 (+ strand)
Transposon Mutants 1 transposon mutants in E264 ATCC 700388

Cross-References

RefSeq YP_439046.1
GI 83717606
Entrez 3846530
GI 83717606
INSDC AIP27396.1
NCBI Locus Tag BTH_RS04410
NCBI Old Locus Tag BTH_II0849
RefSeq WP_011401050.1
UniParc UPI0000667856
UniProtKB Acc A0A096YS09
UniProtKB ID A0A096YS09_BURTA
UniRef100 UniRef100_Q2T703
UniRef50 UniRef50_A3MCH8
UniRef90 UniRef90_A3MCH8

Product

Feature Type CDS
Coding Frame 1
Product Name
BopA protein
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Charge (pH 7) 22.17
Kyte-Doolittle Hydrophobicity Value -0.536
Molecular Weight (kDa) 56486.2
Isoelectric Point (pI) 10.30

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Host Associated
Note: This is based on PSORTb V3.0 secondary localization prediction
Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0428
Category T3SS-3
Evidence ECO:0000250
sequence similarity evidence used in manual assertion
Host Organism
Notes
Annotation transferred from Burkholderia pseudomallei K96243
Reference 17984080

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 3 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG019823 (317 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BTH_II0849
Search term: bopA
Search term: BopA protein

Human Homologs

References

Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592