Burkholderia pseudomallei K96243, BPSS1718 (sdhA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSS1718
Name
sdhA
Replicon chromosome 2
Genomic location 2356776 - 2358551 (- strand)

Cross-References

RefSeq YP_111724.1
GI 53722739
Entrez 3095867
GI 53722739
INSDC CAH39192.1
NCBI Locus Tag BPSS1718
RefSeq YP_111724.1,GeneID
UniParc UPI000043BDD5
UniProtKB Acc Q63JJ8
UniProtKB ID Q63JJ8_BURPS
UniRef100 UniRef100_Q63JJ8
UniRef50 UniRef50_C9Y9P2
UniRef90 UniRef90_Q63JJ8

Product

Feature Type CDS
Coding Frame 1
Product Name
succinate dehydrogenase flavoprotein subunit
Synonyms
Evidence for Translation
Charge (pH 7) 0.38
Kyte-Doolittle Hydrophobicity Value -0.266
Molecular Weight (kDa) 64575.8
Isoelectric Point (pI) 7.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 609 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003068 (662 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1718
Search term: sdhA

Human Homologs

Ensembl 86, assembly GRCh38.p7
succinate dehydrogenase complex flavoprotein subunit A [Source:HGNC Symbol;Acc:HGNC:10680]
E-value: 2.7e-164
Percent Identity: 51.1

References

Quantitative Proteomic Analysis of Burkholderia pseudomallei Bsa Type III Secretion System Effectors Using Hypersecreting Mutants.
Vander Broek CW(1), Chalmers KJ(2), Stevens MP(1), Stevens JM(3).
Mol Cell Proteomics. 2015 Apr;14(4):905-16.
PubMed ID: 25635268