Burkholderia pseudomallei K96243, BPSS1717 (sdhB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSS1717
Name
sdhB
Replicon chromosome 2
Genomic location 2356053 - 2356754 (- strand)

Cross-References

RefSeq YP_111723.1
GI 53722738
Entrez 3095873
GI 53722738
INSDC CAH39191.1
NCBI Locus Tag BPSS1717
RefSeq YP_111723.1,GeneID
UniParc UPI000043BDD4
UniProtKB Acc Q63JJ9
UniProtKB ID Q63JJ9_BURPS
UniRef100 UniRef100_A0A069BAY2
UniRef50 UniRef50_F4PP02
UniRef90 UniRef90_D8P1P8

Product

Feature Type CDS
Coding Frame 1
Product Name
succinate dehydrogenase iron-sulfur subunit
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (30.5 kDa, pI 6.46, PMID:21960737)
Charge (pH 7) -1.61
Kyte-Doolittle Hydrophobicity Value -0.410
Molecular Weight (kDa) 26763.5
Isoelectric Point (pI) 6.27

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
quantitative mass spectrometry evidence
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 470 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003069 (666 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1717
Search term: sdhB

Human Homologs

Ensembl 86, assembly GRCh38.p7
succinate dehydrogenase complex iron sulfur subunit B [Source:HGNC Symbol;Acc:HGNC:10681]
E-value: 1.0e-71
Percent Identity: 58.6

References

Quantitative Proteomic Analysis of Burkholderia pseudomallei Bsa Type III Secretion System Effectors Using Hypersecreting Mutants.
Vander Broek CW(1), Chalmers KJ(2), Stevens MP(1), Stevens JM(3).
Mol Cell Proteomics. 2015 Apr;14(4):905-16.
PubMed ID: 25635268