Burkholderia pseudomallei K96243, BPSS1717 (sdhB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSS1717
Name
sdhB
Replicon chromosome 2
Genomic location 2356053 - 2356754 (- strand)

Cross-References

RefSeq YP_111723.1
GI 53722738
Entrez 3095873
GI 53722738
INSDC CAH39191.1
NCBI Locus Tag BPSS1717
RefSeq YP_111723.1,GeneID
UniParc UPI000043BDD4
UniProtKB Acc Q63JJ9
UniProtKB ID Q63JJ9_BURPS
UniRef100 UniRef100_A0A069BAY2
UniRef50 UniRef50_F4PP02
UniRef90 UniRef90_D8P1P8

Product

Feature Type CDS
Coding Frame 1
Product Name
succinate dehydrogenase iron-sulfur subunit
Synonyms
Evidence for Translation
Detected in B. pseudomallei strain 844 using MALDI-TOF/MS analysis (30.5 kDa, pI 6.46, PMID:21960737)
Charge (pH 7) -1.61
Kyte-Doolittle Hydrophobicity Value -0.410
Molecular Weight (kDa) 26763.5
Isoelectric Point (pI) 6.27

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Extracellular Class 1
quantitative mass spectrometry evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 470 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG003069 (666 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1717
Search term: sdhB

Human Homologs

Ensembl 86, assembly GRCh38.p7
succinate dehydrogenase complex iron sulfur subunit B [Source:HGNC Symbol;Acc:HGNC:10681]
E-value: 1.0e-71
Percent Identity: 58.6

References

Quantitative Proteomic Analysis of Burkholderia pseudomallei Bsa Type III Secretion System Effectors Using Hypersecreting Mutants.
Vander Broek CW(1), Chalmers KJ(2), Stevens MP(1), Stevens JM(3).
Mol Cell Proteomics. 2015 Apr;14(4):905-16.
PubMed ID: 25635268