Strain |
Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest |
Locus Tag |
BPSS1534
|
Name |
bsaZ
Synonym: sctU |
Replicon | chromosome 2 |
Genomic location | 2088082 - 2089317 (- strand) |
Comment | This gene is part of the type III secretion system T3SS-3 (bsa) gene locus. |
RefSeq | YP_111540.1 |
GI | 53722555 |
Entrez | 3096627 |
GI | 53722555 |
INSDC | CAH39007.1 |
NCBI Locus Tag | BPSS1534 |
RefSeq | YP_111540.1,GeneID |
UniParc | UPI000043BD20 |
UniProtKB Acc | Q63K32 |
UniProtKB ID | BSAZ_BURPS |
UniRef100 | UniRef100_Q63K32 |
UniRef50 | UniRef50_Q63K32 |
UniRef90 | UniRef90_Q63K32 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
type III secretion system export apparatus protein BsaZ (T3SS-3)
|
Synonyms |
surface presentation of antigens protein SpaS |
Evidence for Translation | |
Charge (pH 7) | 5.05 |
Kyte-Doolittle Hydrophobicity Value | 0.070 |
Molecular Weight (kDa) | 44457.8 |
Isoelectric Point (pI) | 8.58 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | VFDB : VF0428 |
Category | T3SS-3 |
Evidence |
ECO:0000314
direct assay evidence used in manual assertion
|
Host Organism | |
Notes | |
Reference | 17984080 |
Source 2 | |
Database | Victors : 1987 |
Category | |
Evidence |
ECO:0000015
mutant phenotype evidence
|
Host Organism | Mus musculus |
Notes | bsaZ mutant is attenuated in mouse macrophages |
Reference | 15289563 |
Source 3 | |
Database | BGD |
Category | T3SS-3 |
Evidence |
ECO:0000315
mutant phenotype evidence used in manual assertion
|
Host Organism | Mus musculus |
Notes | bsaZ mutant has reduced intracellular replication in J774.2 murine macrophage-like cells |
Reference | 12410823 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 320 genera
|
Burkholderia Ortholog Group |
BG019837 (326 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BPSS1534
Search term: bsaZ
|
Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592
|
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
|
Burkholderia pseudomallei type III secretion system mutants exhibit delayed vacuolar escape phenotypes in RAW 264.7 murine macrophages.
Burtnick MN, Brett PJ, Nair V, Warawa JM, Woods DE, Gherardini FC
Infect Immun 2008 Jul;76(7):2991-3000
PubMed ID: 18443088
|
Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268
|
An Inv/Mxi-Spa-like type III protein secretion system in Burkholderia pseudomallei modulates intracellular behaviour of the pathogen.
Stevens MP, Wood MW, Taylor LA, Monaghan P, Hawes P, Jones PW, Wallis TS, Galyov EE
Mol Microbiol 2002 Nov;46(3):649-59
PubMed ID: 12410823
|