Strain |
Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest |
Locus Tag |
BPSS1520
|
Name |
bprC
|
Replicon | chromosome 2 |
Genomic location | 2072125 - 2073186 (- strand) |
Comment | This gene is part of the type III secretion system T3SS-3 (bsa) gene locus. In a bprC mutant, the expression of virA and virG was downregulated to 30% and 42%, respectively, whereas tssA expression was decreased to 4% of wild-type level (PMID:20345664). |
RefSeq | YP_111526.1 |
GI | 53722541 |
Entrez | 3095464 |
GI | 53722541 |
NCBI Locus Tag | BPSS1520 |
RefSeq | YP_111526.1,GeneID |
UniProtKB Acc | Q63K46 |
UniProtKB ID | Q63K46_BURPS |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
regulator of type VI secretion system-1 BprC
|
Synonyms |
AraC family transcriptional regulator |
Evidence for Translation | |
Charge (pH 7) | 18.85 |
Kyte-Doolittle Hydrophobicity Value | -0.229 |
Molecular Weight (kDa) | 38910.0 |
Isoelectric Point (pI) | 10.57 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | VFDB : VF0428 |
Category | T3SS-3 |
Evidence |
ECO:0000314
direct assay evidence used in manual assertion
|
Host Organism | |
Notes | |
Reference | 17984080 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 177 genera
|
Burkholderia Ortholog Group |
BG019818 (317 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BPSS1520
Search term: bprC
Search term: regulator of type VI secretion system-1 BprC
|
Unraveling type III secretion systems in the highly versatile Burkholderia pseudomallei.
Sun GW, Gan YH
Trends Microbiol 2010 Dec;18(12):561-8
PubMed ID: 20951592
|
Identification of a regulatory cascade controlling Type III Secretion System 3 gene expression in Burkholderia pseudomallei.
Sun GW, Chen Y, Liu Y, Tan GY, Ong C, Tan P, Gan YH
Mol Microbiol 2010 May;76(3):677-89
PubMed ID: 20345664
|
Regulation of type VI secretion system during Burkholderia pseudomallei infection.
Chen Y, Wong J, Sun GW, Liu Y, Tan GY, Gan YH
Infect Immun 2011 Aug;79(8):3064-73
PubMed ID: 21670170
|
Characterization of BPSS1521 (bprD), a regulator of Burkholderia pseudomallei virulence gene expression in the mouse model.
Chirakul S, Bartpho T, Wongsurawat T, Taweechaisupapong S, Karoonutaisiri N, Talaat AM, Wongratanacheewin S, Ernst RK, Sermswan RW
PLoS One 2014;9(8):e104313
PubMed ID: 25111708
|
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
|