Burkholderia pseudomallei K96243, BPSS1512 (tssM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
Locus Tag
BPSS1512
Name
tssM
Replicon chromosome 2
Genomic location 2065185 - 2066609 (+ strand)

Cross-References

RefSeq YP_111519.1
GI 53722534
Entrez 3096758
GI 53722534
NCBI Locus Tag BPSS1512
RefSeq YP_111519.1,GeneID
UniProtKB Acc Q63K53
UniProtKB ID Q63K53_BURPS

Product

Feature Type CDS
Coding Frame 1
Product Name
deubiquitinase TssM
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 2.04
Kyte-Doolittle Hydrophobicity Value -0.174
Molecular Weight (kDa) 49333.7
Isoelectric Point (pI) 7.45

Subcellular localization

Individual Mappings
Localization Confidence PMID
Extracellular Class 1
Western blot evidence
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 2 genera

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG015371 (28 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: BPSS1512
Search term: tssM

References

Proteomic analysis of the Burkholderia pseudomallei type II secretome reveals hydrolytic enzymes, novel proteins, and the deubiquitinase TssM.
Burtnick MN(1), Brett PJ(1), DeShazer D(2).
Infect Immun. 2014 Aug;82(8):3214-26.
PubMed ID: 24866793
Burkholderia mallei tssM encodes a putative deubiquitinase that is secreted and expressed inside infected RAW 264.7 murine macrophages.
Shanks J(1), Burtnick MN, Brett PJ, Waag DM, Spurgers KB, Ribot WJ, Schell MA, Panchal RG, Gherardini FC, Wilkinson KD, Deshazer D.
Infect Immun. 2009 Apr;77(4):1636-48.
PubMed ID: 19168747